Functional protein mining with conformal guarantees
Ron S. Boger,
Seyone Chithrananda,
Anastasios N. Angelopoulos
et al.
Abstract:1AbstractMolecular structure prediction and homology detection provide a promising path to discovering new protein function and evolutionary relationships. However, current approaches lack statistical reliability assurances, limiting their practical utility for selecting proteins for further experimental and in-silico characterization. To address this challenge, we introduce a novel approach to protein search leveraging principles from conformal prediction, offering a framework that ensures statistical guarant… Show more
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