2017
DOI: 10.1177/0962280217712088
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Functional principal component analysis of glomerular filtration rate curves after kidney transplant

Abstract: This article is motivated by some longitudinal clinical data of kidney transplant recipients, where kidney function progression is recorded as the estimated glomerular filtration rates at multiple time points post kidney transplantation. We propose to use the functional principal component analysis method to explore the major source of variations of glomerular filtration rate curves. We find that the estimated functional principal component scores can be used to cluster glomerular filtration rate curves. Order… Show more

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Cited by 23 publications
(13 citation statements)
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“…This leads to the following weighted least squares solutions (see for example [Gaffney, 2004], [Chamroukhi, 2013], [Faria and Soromenho, 2010]…”
Section: Maximization Stepmentioning
confidence: 99%
See 1 more Smart Citation
“…This leads to the following weighted least squares solutions (see for example [Gaffney, 2004], [Chamroukhi, 2013], [Faria and Soromenho, 2010]…”
Section: Maximization Stepmentioning
confidence: 99%
“…Curve clustering is the process of finding a latent class structure for observations of functional data and has wide applications across industries such as biology, finance and environmental science [Aghabozorgi et al., 2015]. Many methodologies have been developed to deal with such data [Dong et al, 2018]. These methodologies fall into four main methods; shape-based, compression based dissimilarity, feature based, and model-based clustering [Aghabozorgi et al., 2015].…”
Section: Introductionmentioning
confidence: 99%
“…FDA is an effective technique to capture trend and variation modes in functional data (i.e. data providing information about curves, surfaces or anything else varying over a continuum), and has been widely applied in many scientific fields, including behavioural science (Rossi, Wang, and Ramsay 2002), medical research (Dong et al 2018), environmental science (Fraiman et al 2014;Lv, Fowler, and Jing 2019), etc. Furthermore, by taking Ripley's K-function analysis as an example, we also demonstrate how to apply the acquired DI values to adjust ED and correct the biased results of ED-based spatial analysis.…”
Section: Introductionmentioning
confidence: 99%
“…FDA has often been applied in the biological and medical domains (see, for a review, [11]). Recent examples can be found in, e.g., [12][13][14][15].…”
Section: Introductionmentioning
confidence: 99%