Functional Polysaccharides Blended Collagen Cryogels

Odabaş, Sedat

doi:10.15671/hjbc.2018.219

Cited by 2 publications

(2 citation statements)

References 26 publications

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“…Procollagen processing occurs during or shortly after secretion, and then the fibrils are assembled. Finally, the fibrils are stabilized by the formation of covalent crosslinks [22].…”

Section: Biosynthesis Of Collagenmentioning

confidence: 99%

A review on collagen as a food supplement

Musayeva

Özcan

Kaynak

2022

jpt

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One of the most abundant proteins formed in the human body is collagen. It is responsible for the strength of body tissues in all cellular systems by establishing support networks. Collagen fibers are generally opaque and white, due to this reason they are easily recognized in the tissues. Collagen fibers, which are viscoelastic, have low extensibility and high tensile strength. The isoelectric point is around pH 5.8. Collagen is widely used as it helps blood coagulate, remodeling tissue. Although there are no known side effects, there is some concern about its role in inflammation, group-to-group variability, and possible disease transfection, given that animal-derived (natural) collagen is used in many clinical applications. Not every protein is of equal value, so not every collagen is of equal value. Thanks to its low molecular weight, hydrolyzed collagen is quickly digested by our body and enters our blood circulation. According to study, the most suitable type of collagen is the one in powder or liquid form for collagen peptides that can be easily absorbed and used by our body. It is necessary to rely on the most appropriate analysis technique to evaluate the quality feature. Techniques such as SEC, MS, HPLC and NMR are used to characterize complex peptide mixtures. Classical fibril-forming collagen includes collagen types I, II, III, V, and XI. These collagenes are characterized by their ability to aggregate into highly oriented supramolecular aggregates, forming fibrillar arrays with diameters between 25 and 400 nm. Being a natural protein and its technical characteristics, it is expected that development and consumption of collagen hydrolyzate will increase in the coming years. In this review, physical and chemical properties of collagen, types, pharmacology properties, quantity determination methods are briefly described.

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“…Procollagen processing occurs during or shortly after secretion, and then the fibrils are assembled. Finally, the fibrils are stabilized by the formation of covalent crosslinks [22].…”

Section: Biosynthesis Of Collagenmentioning

confidence: 99%

A review on collagen as a food supplement

Musayeva

Özcan

Kaynak

2022

jpt

View full text Add to dashboard Cite

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“…Collagen cryogels with polysaccharide functional components (dextran and carboxymethylcellulose) showed good bio-and hemocompatibility. These cryogels can be used as potential scaffolds for use in tissue engineering and regenerative medicine [62].…”

Section: Restoration Of Cartilage Tissuementioning

confidence: 99%

Untitled

2021

Bull. of the Kar. Univ. "Chem". Ser.

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Biocompatible cryogels: preparation and applicationPolymer cryogels are very promising for producing functional materials. Their porous structure makes them indispensable for some areas of medicine, catalysis, and biotechnology. In this review we focused on methods for producing cryogels based on biopolymers, interpolyelectrolyte complexes of biopolymers, and composite cryogels based on them. First, the properties of cryogels and brief theoretical information about the production of cryogels based on biopolymers were considered. The second section summarizes the latest advances in the production of cryogels based on complexes of biopolymers and composite cryogels. The features of the synthesis and the factors affecting the final properties of materials were considered. In the final part the fields of application of cryogels of the considered types in biotechnology, catalysis and medicine were studied in detail. In biotechnology cryogels are used to immobilize molecules and cells, as a basis for cell growth, and as chromatographic materials for cell separation. In catalysis cryogels are used as a matrix for the immobilization of metal nanoparticles, as well as for the immobilization of enzymes. Biocompatible cryogels and their composites are widely used in medicine for bone and cartilage tissue regeneration, drug delivery, providing a long-term profile of drug release in the body.

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Functional Polysaccharides Blended Collagen Cryogels

Cited by 2 publications

References 26 publications

A review on collagen as a food supplement

A review on collagen as a food supplement

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