Functional outcome of ankle fracture patients treated with biodegradable implants

Rangdal, Sushil; Singh, Daljit; Joshi, Narendra; Soni, Ashwani; Sament, Radheshyam

doi:10.1016/j.fas.2011.05.001

Cited by 13 publications

(12 citation statements)

References 16 publications

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“…Excellent mechanical properties (high specific strength, low density and Young's modulus closing to bones) as well as unique biodegradable behavior of Mg and its alloys in physiological environment make them to be promising candidates as orthopedic and cardiovascular implants [1][2][3], which avoid the necessity of a second removal surgery [4]. In spite of these advantages, biodegradable Mg-based alloys corrode in body fluids too fast to retain mechanical integrity during the whole tissue repair period of 6-12 months [2,5,6].…”

Section: Introductionmentioning

confidence: 99%

Surface characteristics and corrosion resistance of biodegradable magnesium alloy ZK60 modified by Fe ion implantation and deposition

Zheng

Chen

et al. 2014

Progress in Natural Science: Materials International

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The ZK60 magnesium alloy has been modified by Fe ion implantation and deposition with a metal vapor vacuum arc plasma source. The surface morphology, phase constituent and elemental distribution are determined by scanning electron microscopy, transmission electron microscopy, X-ray diffractometer and Auger electron spectroscopy. The results show that Fe thin film is deposited on ZK60 alloy and the corresponding thickness increases from 2.73 μm to 6.36 μm with increasing deposition time. A transition layer mainly composed of Mg, Fe and O elements is formed between Fe thin film and ZK60 substrate. The potentiodynamic polarization tests reveal that a high corrosion potential and a low corrosion current density are detected for the Fe deposited ZK60 alloy, indicating the improvement of corrosion resistance. The tensile deformation test indicates that the Fe deposited film on the ZK60 substrate can sustain 1% tensile strain without any cracks.

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Section: Introductionmentioning

confidence: 99%

Surface characteristics and corrosion resistance of biodegradable magnesium alloy ZK60 modified by Fe ion implantation and deposition

Zheng

Chen

et al. 2014

Progress in Natural Science: Materials International

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“…The aim of operative treatment in ankle fractures is to provide stable internal fixation and allow early motion. Several fixation techniques had been described for the anatomic reduction of fractures, including the Kirschner wire (K-wire) and tension band method, fixation with suture anchors, bioabsorbable screw fixation, a FiberWire loop with a tension band, and bicortical screw fixation [ 1 , 2 , 3 ]. In addition to these techniques, fixation with anterograde screws can also be used for medial malleolar fixation [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Anterograde Headless Cannulated Screw Fixation in the Treatment of Medial Malleolar Fractures: Evaluation of a New Technique and Its Outcomes

et al. 2016

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Objective: To evaluate the functional and radiological outcomes of anterograde headless cannulated screw fixation for medial malleolar fractures. Subjects and Methods: This study included 12 patients (8 males, 4 females; age 27-55 years) with medial malleolar type B fractures according to the Herscovici fracture classification who had undergone anterograde headless cannulated screw fixation surgery between 2012 and 2014. Seven had an isolated medial malleolar fracture and 5 a bimalleolar fracture. All of the bimalleolar fractures were classified as 44-B2 based on the Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association (AO/OTA) classification. Postoperatively, bone union was evaluated on direct radiographs at the final follow-up examination. The American Orthopaedic Foot and Ankle Society (AOFAS) scoring system was used for clinical evaluation. Results: The mean follow-up period was 17.2 ± 5.3 months (range 12-23). Full union was achieved in all fractures. The mean time to union was 3.4 ± 1.5 months (range 2-5). No instability, loss of reduction, non-union or infection was observed in any patient. The mean AOFAS score was 95.0 ± 5.4 (range 87-99). Based on the AOFAS score, 4 patients showed good results and 8 excellent results. The mean time to return to the previous level of activity was 4.0 ± 2.5 months (range 2-5). Conclusion: In this study, anterograde headless cannulated screw fixation yielded good clinical outcome in the surgical treatment of Herscovici type B fractures.

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“…Although the studies did not demonstrate significant differences in postoperative complications, absorbable polymers are mechanically weaker, and their degradation process through hydrolysis resulted in acidic elements, which can increase infections and bone resorption osteoclasts activation. The findings indicated that the use of PLLA and PGA might not be applicable for clinical applications, and the search for other degradable materials is warranted [ 14 , 73 , 74 , 75 ].…”

Section: Discussionmentioning

confidence: 99%

Is There a Role for Absorbable Metals in Surgery? A Systematic Review and Meta-Analysis of Mg/Mg Alloy Based Implants

et al. 2020

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Magnesium (Mg) alloys have received attention in the literature as potential biomaterials for use as absorbable implants in oral and maxillofacial and orthopedic surgery applications. This study aimed to evaluate the available clinical studies related to patients who underwent bone fixation (patients), and received conventional fixation (intervention), in comparison to absorbable metals (comparison), in terms of follow-up and complications (outcomes). A systematic review and meta-analysis were performed in accordance with the PRISMA statement and PROSPERO (CRD42020188654), PICO question, ROBINS-I, and ROB scales. The relative risk (RR) of complications and failures were calculated considering a confidence interval (CI) of 95%. Eight studies (three randomized clinical trial (RCT), one retrospective studies, two case-control studies, and two prospective studies) involving 468 patients, including 230 Mg screws and 213 Titanium (Ti) screws, were analyzed. The meta-analysis did not show any significant differences when comparing the use of Mg and Ti screws for complications (p = 0.868). The estimated complication rate was 13.3% (95% CI: 8.3% to 20.6%) for the comparison group who received an absorbable Mg screw. The use of absorbable metals is feasible for clinical applications in bone surgery with equivalent outcomes to standard metal fixation devices.

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Functional outcome of ankle fracture patients treated with biodegradable implants

Cited by 13 publications

References 16 publications

Surface characteristics and corrosion resistance of biodegradable magnesium alloy ZK60 modified by Fe ion implantation and deposition

Surface characteristics and corrosion resistance of biodegradable magnesium alloy ZK60 modified by Fe ion implantation and deposition

Anterograde Headless Cannulated Screw Fixation in the Treatment of Medial Malleolar Fractures: Evaluation of a New Technique and Its Outcomes

Is There a Role for Absorbable Metals in Surgery? A Systematic Review and Meta-Analysis of Mg/Mg Alloy Based Implants

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