Functional measurement of collateral ventilation is of additional value to CT scan fissure analysis in endobronchial valve treatment for emphysema

Klooster, Karin; Koster, D.; Gloesenkamp, Christoph R.; Theilig, Dorothea; Suttorp, Norbert; Slebos, Dirk‐Jan; Huebner, Ralf-Harto

doi:10.1183/13993003.congress-2019.pa3405

Cited by 2 publications

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“…Early studies suggested that together, computer analysis of the HRCT and the Chartis ® assessment have a pooled sensitivity of 75% for detecting CV (30). Recent data have shown that for the left and right major fissures, a FCS >95% has a sensitivity of 91.1% and 73.7%, respectively (31). Thus, Chartis ® assessment is recommended on the right regardless of quantitative CT fissure analysis.…”

Section: Patient Selectionmentioning

confidence: 99%

Bronchoscopic lung volume reduction: who, what, where, when?

Kurman¹,

Hogarth²

2021

Shanghai Chest

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Chronic obstructive pulmonary disease (COPD) is a significant source of morbidity and mortality globally. The number of afflicted individuals is expected to increase for the foreseeable future. Endoscopic lung volume reduction (ELVR) modalities have recently been introduced as an alternative to more invasive lung volume reduction surgery (LVRS) for severe emphysema. Endoscopic tools include one-way valves, coils, thermal vapor ablation, and sealant. These devices are broadly classified as "block" and "non-block" strategies. They differ in terms of the requirement for fissure integrity, whether they are applied at the lobar or segmental level, their reversibility, and whether they are applicable for homogenous and/or heterogenous disease. Endobronchial valves (EBVs) are now being used outside of clinical trials and are supported by multiple guidelines. These valves reduce hyperinflation by promoting lobar atelectasis in the absence of collateral ventilation (CV), which can now be quantified using specialized software and intra-procedural analysis. Patient selection criteria continue to be refined as more data become available. Pneumothorax is the most common adverse event but does not appear to affect outcomes if it is appropriately managed. Multiple ongoing trials are investigating the impact of different devices and strategies in order to improve long-term outcomes. Other modalities for ELVR are under development. Herein, we review the impact of COPD on population health and discuss the role of endobronchial procedural interventions in its management.

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Section: Patient Selectionmentioning

confidence: 99%

Bronchoscopic lung volume reduction: who, what, where, when?

Kurman¹,

Hogarth²

2021

Shanghai Chest

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“…At the ERS International Congress, multiple studies investigated patient and target lobe selection for valve therapy to increase treatment success and prevent inappropriate treatments. Comparing quantitative CT fissure analysis with invasive catheter-based Chartis (Pulmonx Inc., Redwood City, CA, USA) measurement showed an additional benefit with use of the Chartis procedure [ 14 ]. For the left major fissure, a fissure completeness of >95% on CT had a positive predictive value of 91%, whereas a fissure completeness ≤83% had a sensitivity of 100%.…”

Section: Group 1401: Interventional Pulmonologymentioning

confidence: 99%

ERS International Congress, Madrid, 2019: highlights from the Clinical Techniques, Imaging and Endoscopy Assembly

d'Hooghe¹,

Martinez²,

Pietersen³

et al. 2020

ERJ Open Res

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This manuscript summarises the highlights from Assembly 14, “Clinical techniques, imaging and endoscopy”, which were presented at the 2019 European Respiratory Society (ERS) International Congress in Madrid, Spain. Novel diagnostic approaches and innovative therapeutic strategies in patients with lung cancer, interstitial lung disease, obstructive airway disorders and infectious diseases are discussed. The authors from the different Assembly 14 subgroups focus on the key take-home messages given new study results, and place them in the context of current knowledge in these areas.At the 2019 ERS International Congress, encouraging results of numerous trials in the field of interventional pulmonology, imaging and ultrasound were presented. Key topics included novel diagnostic and therapeutic approaches in patients with lung cancer, interstitial lung disease, obstructive airway disorders and infectious diseases.

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Functional measurement of collateral ventilation is of additional value to CT scan fissure analysis in endobronchial valve treatment for emphysema

Cited by 2 publications

References 0 publications

Bronchoscopic lung volume reduction: who, what, where, when?

Bronchoscopic lung volume reduction: who, what, where, when?

ERS International Congress, Madrid, 2019: highlights from the Clinical Techniques, Imaging and Endoscopy Assembly

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