Functional Liver Imaging Score derived from gadoxetic acid-enhanced MRI predicts outcomes in patients with chronic liver disease

Magnetic resonance‐based biomarkers in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

“…Several studies have been performed utilizing dynamic imaging with gadoxetate disodium, 79,80 and this allows quantitative information to be extracted by compartmental modelling yielding data on uptake and excretion rate of gadoxetate disodium in the hepatocytes but also quantitative assessment of extracellular volume in the liver, the same parameter that is associated with T1 but here directly quantified. Emerging data recently presented at the International Liver Congress in 2019 have assessed the predictive value of gadoxetate disodium imaging in patients with compensated (N = 110) and decompensated (N = 99) cirrhosis and have reported good prognostic information in both groups with a follow‐up time of 48 months 81 . However, the following drawbacks need to be considered.…”