Functional level of patients with chronic fatigue syndrome reporting use of alternative vs. traditional treatments

Wise, Shelby; Jantke, Rachel; Brown, Abigail; Jason, Leonard A.

doi:10.1080/21641846.2015.1097102

Cited by 4 publications

(4 citation statements)

References 17 publications

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“…Mind-body techniques have been used by individuals as a treatment many of the symptoms experienced by those with PASC [157][158][159] and have the potential to bring about structural and functional changes to the brain. 3,155 Investigators and practitioners are beginning to explore the use of meditation for those with PASC.…”

Section: Discussionmentioning

confidence: 99%

“…34 Mind-body techniques have been used by individuals as a remedy for symptoms related to the brain and cognitive dysfunctions. [157][158][159] Meditation has been demonstrated to cause neural reorganization and re-regulation in both novices and long-term practitioners. 34,160 These studies on the neurochemical effects of meditation on neurotransmitters, coupled with the established research on salutogenic immune profiles of meditators, 72 indicate several wide-ranging neuroimmune benefits of a regular practice of meditation.…”

Section: Neurological Effects Of Meditationmentioning

confidence: 99%

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Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune Functioning

Porter¹,

Jason²

2022

NDT

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Some individuals infected with SARS CoV-2 have developed Post-Acute Sequelae of SARS CoV-2 infection (PASC) or what has been referred to as Long COVID. Efforts are underway to find effective treatment strategies for those with Long COVID. One possible approach involves alternative medical interventions, which have been widely used to treat and manage symptoms of a variety of medical problems including post-viral infections. Meditation has been found to reduce fatigue and unrefreshing sleep, and for those with post-viral infections, it has enhanced immunity, and reduced inflammatory-driven pathogenesis. Our article summarizes the literature on what is known about mindfulness meditation interventions, and reviews evidence on how it may apply to those with Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Evidence is reviewed suggesting effective and sustainable outcomes may be achieved for symptomatology and underlying pathology of post-viral fatigue (PASC and ME/CFS).

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Section: Discussionmentioning

confidence: 99%

Section: Neurological Effects Of Meditationmentioning

confidence: 99%

Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune Functioning

Porter¹,

Jason²

2022

NDT

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“…It is thought that the effects of meditation rely on the body’s ability to switch to α (resting) or theta brain-wave states, and during meditation the brain’s rhythm slows appreciably and endorphins are released (Goleman & Davidson, 2017). Psychologists could use these types of mind–body techniques as a treatment for postviral symptoms of fatigue and cognitive dysfunction (Centers for Disease Control & Prevention, 2019; Wise et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Using systems theory to improve intervention outcomes.

Jason¹,

Bobak²

2022

Professional Psychology: Research and Practice

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This article explores the potential of using systems methods for better conceptualizing the unexpected and complex sets of hurdles and opportunities that practicing psychologists frequently encounter. Examples are provided involving two distinct types of important clinical issues: (a) understanding how individuals maintain recovery from substance use disorders following treatment and (b) better understanding patients with chronic, unexplained postviral illnesses. Traditional research methods used to explore these types of intricate social and medical issues have often lacked sophisticated dynamic systems-based perspectives, which could provide new insights into understanding how patient treatment gains can be maintained and how unexplained postviral illnesses can be better understood. Our examples will demonstrate that systemsoriented approaches have the potential to provide psychologists unique opportunities to capture a fuller and richer depiction of a variety of clinical and community topics and thus provide new lenses that ultimately could provide better care for our patients. Public Significance StatementSystems research and community psychology can be applied in understanding complex behavioral phenomena. It thus provides a useful perspective to practitioners in assisting with solutions to psychological or societal problems.

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“…The mind-body technics have also been demonstrated to induce a neural reorganization in practitioners [ 171 ], therefore these interventional methods are applicable to patients as a therapy for symptoms related to the brain and cognitive dysfunctions as well as support for psychosocial complications [ 177 , 178 ]. Some studies investigating effects of meditation on neurotransmitters and immune profiles of meditators [ 169 ] found various wide-ranging neuroimmune benefits by applying meditation on a regular basis.…”

Section: Search For Therapeutic Strategies: Modulatory Effect Of Bioa...mentioning

confidence: 99%

Aged brain and neuroimmune responses to COVID-19: post-acute sequelae and modulatory effects of behavioral and nutritional interventions

Müller

Benedetto

2023

Immun Ageing

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Advanced age is one of the significant risk determinants for coronavirus disease 2019 (COVID-19)-related mortality and for long COVID complications. The contributing factors may include the age-related dynamical remodeling of the immune system, known as immunosenescence and chronic low-grade systemic inflammation. Both of these factors may induce an inflammatory milieu in the aged brain and drive the changes in the microenvironment of neurons and microglia, which are characterized by a general condition of chronic inflammation, so-called neuroinflammation. Emerging evidence reveals that the immune privilege in the aging brain may be compromised. Resident brain cells, such as astrocytes, neurons, oligodendrocytes and microglia, but also infiltrating immune cells, such as monocytes, T cells and macrophages participate in the complex intercellular networks and multiple reciprocal interactions. Especially changes in microglia playing a regulatory role in inflammation, contribute to disturbing of the brain homeostasis and to impairments of the neuroimmune responses. Neuroinflammation may trigger structural damage, diminish regeneration, induce neuronal cell death, modulate synaptic remodeling and in this manner negatively interfere with the brain functions.In this review article, we give insights into neuroimmune interactions in the aged brain and highlight the impact of COVID-19 on the functional systems already modulated by immunosenescence and neuroinflammation. We discuss the potential ways of these interactions with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and review proposed neuroimmune mechanisms and biological factors that may contribute to the development of persisting long COVID conditions. We summarize the potential mechanisms responsible for long COVID, including inflammation, autoimmunity, direct virus-mediated cytotoxicity, hypercoagulation, mitochondrial failure, dysbiosis, and the reactivation of other persisting viruses, such as the Cytomegalovirus (CMV). Finally, we discuss the effects of various interventional options that can decrease the propagation of biological, physiological, and psychosocial stressors that are responsible for neuroimmune activation and which may inhibit the triggering of unbalanced inflammatory responses. We highlight the modulatory effects of bioactive nutritional compounds along with the multimodal benefits of behavioral interventions and moderate exercise, which can be applied as postinfectious interventions in order to improve brain health.

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Functional level of patients with chronic fatigue syndrome reporting use of alternative vs. traditional treatments

Cited by 4 publications

References 17 publications

Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune Functioning

Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune Functioning

Using systems theory to improve intervention outcomes.

Aged brain and neuroimmune responses to COVID-19: post-acute sequelae and modulatory effects of behavioral and nutritional interventions

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