Functional lateralization of arithmetic processing in the intraparietal sulcus is associated with handedness

Artemenko, Christina; Sitnikova, Maria; Soltanlou, Mojtaba; Dresler, Thomas; Nuerk, Hans‐Christoph

doi:10.1038/s41598-020-58477-7

Cited by 21 publications

(15 citation statements)

References 93 publications

(93 reference statements)

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“…While the right intraparietal sulcus is engaged in non-symbolic number magnitude processing, particularly at early ages (Edwards et al 2016;Hyde et al 2010), the left intraparietal sulcus is deeply involved in symbolic number magnitude processing of the numbers at school ages (Vogel et al 2015) in association with language-related areas on the left hemisphere. Supporting our current finding, the right parietal cortex is expected to be involved in the calculation to a greater degree in younger children than the left parietal cortex, according to a recent theoretical model of functional lateralization in the parietal cortex in arithmetic (Artemenko et al 2020).…”

Section: Neurobehavioral Changes During Complex Calculation In Childr...supporting

confidence: 87%

Training causes activation increase in temporo-parietal and parietal regions in children with mathematical disabilities

et al. 2022

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While arithmetic training reduces fronto-temporo-parietal activation related to domain-general processes in typically developing (TD) children, we know very little about the training-related neurocognitive changes in children with mathematical disabilities (MD), who seek evidenced-based educational interventions. In a within-participant design, a group of 20 children (age range = 10–15 years old) with MD underwent 2 weeks of arithmetic training. Brain activation was measured using functional near-infrared spectroscopy (fNIRS) before and after training to assess training-related changes. Two weeks of training led to both behavioral and brain changes. Training-specific change for trained versus untrained (control) simple multiplication solving was observed as activation increase in the bilateral temporo-parietal region including angular gyrus and middle temporal gyrus. Training-specific change for trained versus untrained (control) complex multiplication solving was observed as activation increase in the bilateral parietal region including intraparietal sulcus, superior parietal lobule, and supramarginal gyrus. Unlike the findings of a similar study in TD children, 2 weeks of multiplication training led to brain activation increase in the fronto-parietal network in children with MD. Interestingly, these brain activation differences between the current findings and a recent similar study in TD children underlie a rather similar behavioral improvement as regards response time and accuracy after 2 weeks of training. This finding provides valuable insights into underlying mechanisms of mathematics learning in special samples and suggests that the findings in TD children may not be readily generalized to children with MD.

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Section: Neurobehavioral Changes During Complex Calculation In Childr...supporting

confidence: 87%

Training causes activation increase in temporo-parietal and parietal regions in children with mathematical disabilities

et al. 2022

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“…The other major finding-reduced WM coherence and shorter length of the left anterior thalamic radiation-might be attributed to insufficiencies in encoding, retrieving and working with arithmetical facts in children with DD. Left lateralized differences in these pathways might be related to hemispheric dominance, which was proposed to be pronounced in arithmetic processing during development (Artemenko et al, 2020). In this neurodevelopmental study, we revealed first evidence that lower math performance corresponded with lower WM coherence and shorter pathways.…”

Section: Discussionmentioning

confidence: 54%

Structural brain connectivity in children with developmental dyscalculia

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Beyer

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et al. 2021

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Developmental dyscalculia (DD) is a neurodevelopmental disorder specific to arithmetic learning even with normal intelligence and age-appropriate education. Difficulties often persist from childhood through adulthood. Underlying neurobiological mechanisms of DD, however, are poorly understood. This study aimed to identify possible structural connectivity alterations in DD. We evaluated 10 children with pure DD (11.3 plus-or-minus sign 0.7 years) and 16 typically developing (TD) peers (11.2 plus-or-minus sign 0.6 years) using diffusion tensor imaging. We first assessed white matter microstructure with tract-based spatial statistics. Then we used probabilistic tractography to evaluate tract lengths and probabilistic connectivity maps in specific regions. At whole brain level, we found no significant microstructural differences in white matter between children with DD and TD peers. Also, seed-based connectivity probabilities did not differ between groups. However, we did find significant differences in regions-of-interest tracts which had previously been related to math ability in children. The major findings of our study were reduced white matter coherence and shorter tract lengths of the left superior longitudinal/arcuate fasciculus and left anterior thalamic radiation in the DD group. Furthermore, lower white matter coherence and shorter pathways corresponded with the lower math performance as a result of the correlation analyses. These results from regional analyses indicate that learning, memory and language-related pathways in the left hemisphere might underlie DD. Keywords: Mathematical learning disability, diffusion tensor imaging, superior longitudinal fasciculus, anterior thalamic radiation, probabilistic tractography, tract-based spatial statistics

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“…Handedness has also been linked to performance in several tasks: in auditory coordination tasks, participants respond faster to stimuli presented on the side contralateral to their preferred hand (Ocklenburg et al 2010). Similarly, in arithmetic processing tasks, left-handers show stronger functional right-sided activity than right-handers (Artemenko et al 2020). Furthermore, approach motivation was found to be associated with left-hemispheric activity in right-handers and right-hemispheric activity in left-handers (Brookshire and Casasanto 2012).…”

Section: Introductionmentioning

confidence: 99%

Frontal and parietal EEG alpha asymmetry: a large-scale investigation of short-term reliability on distinct EEG systems

et al. 2021

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EEG resting-state alpha asymmetry is one of the most widely investigated forms of functional hemispheric asymmetries in both basic and clinical neuroscience. However, studies yield inconsistent results. One crucial prerequisite to obtain reproducible results is the reliability of the index of interest. There is a body of research suggesting a moderate-to-good reliability of EEG resting-state alpha asymmetry, but unfortunately sample sizes in these studies are typically small. This study presents the first large-scale short-term reliability study of frontal and parietal EEG resting-state alpha asymmetry. We used the Dortmund Vital Study data set containing 370 participants. In each participant, EEG resting state was recorded eight times, twice with their eyes opened, twice with their eyes-closed, each on two different EEG systems. We found good reliability of EEG alpha power and alpha asymmetry on both systems for electrode pairs. We also found that alpha power asymmetry reliability is higher in the eyes-closed condition than in the eyes-open condition. The frontomedial electrode pair showed weaker reliability than the frontolateral and parietal electrode pairs. Interestingly, we found no population-level alpha asymmetry in frontal electrodes, one of the most investigated electrode sites in alpha asymmetry research. In conclusion, our results suggest that while EEG alpha asymmetry is an overall reliable measure, frontal alpha asymmetry should be assessed using multiple electrode pairs.

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Functional lateralization of arithmetic processing in the intraparietal sulcus is associated with handedness

Cited by 21 publications

References 93 publications

Training causes activation increase in temporo-parietal and parietal regions in children with mathematical disabilities

Training causes activation increase in temporo-parietal and parietal regions in children with mathematical disabilities

Structural brain connectivity in children with developmental dyscalculia

Frontal and parietal EEG alpha asymmetry: a large-scale investigation of short-term reliability on distinct EEG systems

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