Functional, Ischemic Mitral Regurgitation

Randomized Trials in Moderate Ischemic Mitral Regurgitation

“…Opinions vary strongly regarding the use of routinely adding mitral valve repair (MVRp) with a downsized rigid or semirigid annuloplasty ring to coronary revascularization in patients with moderate ischemic MR referred for coronary artery bypass graft (CABG) surgery. [11][12][13][14][15] In a minority of patients, moderate ischemic MR improves or resolves after coronary revascularization alone, possibly in association with the viability of subjacent myocardium and absence of papillary muscle dyssynchrony. 16 Efforts to identify these patients confidently have been sporadic.…”

Ring annuloplasty for ischemic mitral regurgitation: A single center experience

“…Several researchers have shown that IMR progresses after CABG alone, and yields poor survival rates on long-term follow-up. 10 Mallidi and colleagues 9 reported the progression of mild to moderate IMR to severe MR in 30% of patients undergoing CABG alone. According to the Society of Thoracic Surgeons database, concomitant mitral valve surgery may be the treatment of choice in low-risk patients with mild to moderate mitral regurgitation.…”

New Insights in the Diagnosis and Treatment of Heart Failure

“…Trichon and coworkers analyzed a wide series of patients with ischemic FMR and found that PCI, CABG, and CABG plus MV repair all obtained a 3-year survival advantage compared to medical therapy in this subset of patients [ 88 ]. A retrospective study from the Brigham and Women's Hospital in Boston recently reported an improved survival of patients undergoing mitral valve repair for cardiomyopathy [ 89 ]. A recent analysis of more than 1,200 patients enrolled in the STICH Trial for ischemic cardiomyopathy demonstrated that concomitant MV repair in patients with moderate-to-severe FMR who underwent CABG reduces 30-day mortality compared to either patients undergoing isolated CABG or those medically treated [ 90 ].…”