2020
DOI: 10.1136/jisakos-2019-000386
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Functional improvement and low recurrence rate after combined staged synovectomy and external radiotherapy for diffuse pigmented villonodular synovitis of the knee: a minimum 2 years' follow-up case series

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“…As stated in the literature, tumor resection and synovectomy-only approach could induce a higher recurrence rate; the least average time to revision surgery is 6.5 years [17]. Applying adjuvant radiotherapy for PVNS is under debate [1,29]; synovectomy and added external radiotherapy showed some functional improvement and improvement in patients' quality of lives with a low rate of lesion recurrence in the knee [30]. However, efficacy is unconfirmed and there is caution against unwelcome irradiation effects around the reproductive organs, e.g., the hip and pelvis [6,31,32].…”
Section: Discussionmentioning
confidence: 99%
“…As stated in the literature, tumor resection and synovectomy-only approach could induce a higher recurrence rate; the least average time to revision surgery is 6.5 years [17]. Applying adjuvant radiotherapy for PVNS is under debate [1,29]; synovectomy and added external radiotherapy showed some functional improvement and improvement in patients' quality of lives with a low rate of lesion recurrence in the knee [30]. However, efficacy is unconfirmed and there is caution against unwelcome irradiation effects around the reproductive organs, e.g., the hip and pelvis [6,31,32].…”
Section: Discussionmentioning
confidence: 99%