Functional Hybrid Micro/Nanoentities Promote Agro-Food Safety Inspection

Abstract

The rapid development of nanomaterials has provided a good theoretical basis and technical support to solve the problems of food safety inspection. The combination of functionalized composite nanomaterials and well-known detection methods is gradually applied to detect hazardous substances, such as chemical residues and toxins, in agricultural food products. This review concentrates on the latest agro-food safety inspection techniques and methodologies constructed with the assistance of new hybrid micro/nanoentities, such as molecular imprinting polymers integrated with quantum dots (MIPs@QDs), molecular imprinting polymers integrated with upconversion luminescent nanoparticles (MIPs@UCNPs), upconversion luminescent nanoparticles combined with metal−organic frameworks (UCNPs@MOFs), magnetic metal−organic frameworks (MOFs@Fe 3 O 4 ), magnetic covalent−organic frameworks (Fe 3 O 4 @COFs), covalent−organic frameworks doped with quantum dots (COFs@QDs), nanobodyinvolved immunoassay for fast inspection, etc. The presented summary and discussion favor a relevant outlook for further integrating various disciplines, like material science, nanotechnology, and analytical methodology, for addressing new challenges that emerge in agro-food research fields.

Current Scenario of Pathogen Detection Techniques in Agro-Food Sector

“…In the case of food products, MIPs have been employed for the determination of a large variety of hazards such as small molecules (mycotoxins), macromolecules (allergenic pro- In comparison to other receptors such as enzymes or antibodies, MIPs offer several interesting properties in terms of chemical and physical stability and reusability [80]. In the case of food products, MIPs have been employed for the determination of a large variety of hazards such as small molecules (mycotoxins), macromolecules (allergenic proteins), and larger analytes (pathogenic bacteria) [81]. In comparison to small molecules, bacterial detection faces several scientific challenges due to their intrinsic properties such as fragile structure, large size, poor stability in organic solvents, and fluidity [82].…”

Metal-porphyrinic framework nanotechnologies in modern agricultural management

“…As mentioned above, the challenges associated with the development of such applied nano-MOFs are, again, motivated by crucial agro-food security and supply factors while keeping obvious environmental issues a priority. 20 Incidentally, biodegradable MOFs have also been recently developed for various health related issues, [21][22][23] including food safety, 24 and their conception can also be applied to agricultural purposes.…”

Magnetically Controlled Nanorobots Based on Red Emissive Peptide Dots and Artificial Antibodies for Specific Recognition and Smart Scavenging of Nε-(Carboxymethyl)lysine in Dairy Products

“…14 Recently, optosensing platforms based on artificial antibodies and fluorescent signal materials such as organic dyes, quantum dots, and upconversion nanoparticles, have been applied to identify and quantify target food contamination in a real time and in situ manner. 15,16 Owing to the imprinted hollows matching with the target molecule in size, shape, and functional group, artificial antibodies created by molecularly imprinted technologies displayed a high selectivity and specificity toward the target. 17 Meanwhile, the changes in emission intensity provided by fluorescent signal materials serve as indicators to detect the content of the target molecule.…”