Functional foods with digestion-enhancing properties

Valussi, Marco

doi:10.3109/09637486.2011.627841

Cited by 31 publications

(29 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Different from previously published work [1], [3]–[5], ginger had no antiemetic effect on any of the outcome measures in our rotation chair procedure. Also, the ginger information per se was not effective in preventing or reducing motion sickness or in affecting behavioral and physiological measures.…”

Section: Discussioncontrasting

confidence: 99%

See 1 more Smart Citation

Effects of Ginger and Expectations on Symptoms of Nausea in a Balanced Placebo Design

Weimer¹,

Schulte²,

Maichle³

et al. 2012

PLoS ONE

View full text Add to dashboard Cite

ObjectiveGinger effects on (experimental) nausea have been described, but also strong placebo effects and sex differences when nausea is involved. The “balanced placebo design” has been proposed to allow better separation of drug and placebo effects.MethodsSixty-four healthy participants (32 women) were randomly assigned to receive an antiemetic ginger preparation or placebo, and half of each group was told to have received drug or placebo. They were exposed to 5×2 min body rotations to induce nausea. Subjective symptoms and behavioral (rotation tolerance, head movements) and physiological measures (electrogastrogram, cortisol) were recorded. Groups were balanced for sex of participants and experimenters.ResultsGinger and the information given did not affect any outcome measure, and previous sex differences could not be confirmed. Adding the experimenters revealed a significant four-factorial interaction on behavioral but not on subjective or physiological measures Men who received placebo responded to placebo information when provided by the male experimenter, and to ginger information when provided by the female experimenter. This effect was not significant in women.ConclusionThe effects of an antiemetic drug and provided information interact with psychosocial variables of participants and experimenters in reports of nausea.

show abstract

Section: Discussioncontrasting

confidence: 99%

“…Herbal and alternative medicine remedies such as ginger [1] are widely used and accepted [2] for the treatment of the various clinical conditions associated with nausea, e.g. in motion and sea sickness [3], chemotherapy-induced nausea [4], and pregnancy [5]; however, efficacy data have remained controversial [6].…”

Section: Introductionmentioning

confidence: 99%

Effects of Ginger and Expectations on Symptoms of Nausea in a Balanced Placebo Design

Weimer¹,

Schulte²,

Maichle³

et al. 2012

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Chamomile and Melissa extracts have many effects including mild sedative and carminative, spasmolytic, antibacterial, antiviral, and antioxidative effects [50]. The polyphenols present in chamomile and melissa are flavonoids containing quercetin, luteolin, apigenine-like and other substances with similar chemical characteristics that allow the compound to become a preferential substrate for free radicals, with radical scavenger action [51].…”

Section: Discussionmentioning

confidence: 99%

Researching New Therapeutic Approaches for Abdominal Visceral Pain Treatment: Preclinical Effects of an Assembled System of Molecules of Vegetal Origin

Parisio,

Lucarini,

Micheli

et al. 2019

Nutrients

View full text Add to dashboard Cite

Abdominal pain is a frequent symptom of irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBDs). Although the knowledge of these pathologies is progressing, new therapeutic strategies continue to be investigated. In the present study, the effect of a system of molecules of natural origin (a medical device according to EU Directive 93/42/EC, engineered starting from Boswellia serrata resins, Aloe vera polysaccharides and Matricaria chamomilla and Melissa officinalis polyphenols) was evaluated against the intestinal damage and visceral pain development in DNBS-induced colitis model in rats. The system (250 and 500 mg kg−1) was orally administered once daily, starting three days before the injection of 2,4-dinitrobenzenesulfonic acid (DNBS) and for 14 days thereafter. The viscero-motor response (VMR) to colon-rectal balloon distension (CRD) was used as measure of visceral sensitivity. The product significantly reduced the VMR of DNBS-treated animals. Its effect on pain threshold was better than dexamethasone and mesalazine, and not lower than amitriptyline and otilonium bromide. At microscopic and macroscopic level, the tested system was more effective in protecting the intestinal mucosa than dexamethasone and mesalazine, promoting the healing of tissue lesions. Therefore, we suggest that the described system of molecules of natural origin may represent a therapeutic option to manage painful bowel diseases.

show abstract

“…Stool testing revealed no pathogenic organisms, however, there was evidence of lipid malabsorption as measured by fecal phospholipids and cholesterol.At week six of the program, the participant was counseled to increase the consumption of fish rich in omega-3 fatty acids, folate-rich foods, as well as glycine-rich foods such as bone broth. She was encouraged to explore the use of AIP-complaint digestive bitters to assist in the digestion and absorption of nutrients [27]. Following the program, the participant’s MSQ decreased from 98 to 12 with no further severe symptoms.…”

Section: Tablementioning

confidence: 99%

Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto’s Thyroiditis

Abbott¹,

Sadowski

Alt

2019

Cureus

View full text Add to dashboard Cite

Background Hashimoto’s thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is an autoimmune disorder affecting the thyroid gland and is the most common cause of hypothyroidism in the US. Despite medical management with thyroid hormone replacement, many individuals with HT continue to experience symptoms and impaired quality of life. Given the limited number of efficacious treatments outside of hormone replacement and the overall burden of continued symptomatic disease, this pilot study was designed to determine the efficacy of a multi-disciplinary diet and lifestyle intervention for improving the quality of life, clinical symptom burden, and thyroid function in a population of middle-aged women with HT. Materials and methods The study recruited 17 normal or overweight (body mass index (BMI) <29.9) female subjects between the ages of 20 and 45 with a prior diagnosis of HT. The 17 women participated in a 10-week online health coaching program focused on the implementation of a phased elimination diet known as the Autoimmune Protocol (AIP). The 36-Item Short Form Health Survey (SF-36) and Cleveland Clinic Center for Functional Medicine’s Medical Symptoms Questionnaire (MSQ) were used to measure the participant’s health-related quality of life (HRQL) and clinical symptom burden, respectively, before and after the 10-week program. The participants completed serologic testing that included a complete blood cell count (CBC) with differential, complete metabolic profile (CMP), thyroid function tests, including thyroid stimulating hormone (TSH), total and free T4, and total and free T3, thyroid antibodies, including thyroid peroxidase antibodies (TPO) and anti-thyroglobulin antibodies (TGA), and high-sensitivity C-reactive protein (hs-CRP). Results Sixteen women (n = 16) completed the SF-36 and MSQ before and after the 10-week program. There was a statistically significant improvement in HRQL as measured by all eight subscales of the SF-36 with the most marked improvements noted in the physical role functioning, emotional role functioning, vitality, and general health subscales. The clinical symptom burden, as measured by the MSQ, decreased significantly from an average of 92 (SD 25) prior to the program to 29 (SD 20) after the program. There were no statistically significant changes noted in any measure of thyroid function, including TSH, free and total T4, free and total T3 (n = 12), as well as thyroid antibodies (n = 14). Inflammation, as measured by hs-CRP (n = 14), was noted to significantly decrease by 29% (p = 0.0219) from an average of 1.63 mg/L (SD 1.72) pre-intervention to 1.15 mg/L (SD 1.31) post-intervention. Conclusions Our study suggests that an online diet and lifestyle program facilitated by a multi-disciplinary team can significantly improve HRQL and symptom burden in middle-aged female subjects with HT. While there were no statistically significant changes noted in thyroid function or thyroid antibodies, the s...

show abstract

Functional foods with digestion-enhancing properties

Cited by 31 publications

References 29 publications

Effects of Ginger and Expectations on Symptoms of Nausea in a Balanced Placebo Design

Effects of Ginger and Expectations on Symptoms of Nausea in a Balanced Placebo Design

Researching New Therapeutic Approaches for Abdominal Visceral Pain Treatment: Preclinical Effects of an Assembled System of Molecules of Vegetal Origin

Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto’s Thyroiditis

Contact Info

Product

Resources

About