Functional capacity and ventilatory efficiency are preserved in well-controlled people living with human immunodeficiency virus/acquired immunodeficiency syndrome

Abstract

To verify and compare the responses of the cardiopulmonary variables to the incremental test in physically inactive people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) (PLWHA) with well-controlled disease and physically inactive healthy subjects (non-HIV/AIDS). Participants performed a cardiopulmonary exercise test (CPX) on a treadmill. Data were analyzed using the Mann–Whitney test and Spearman correlation. Nine PLWHA (5 women) and 9 non-HIV/AIDS gender and activity level-matched controls were included in the data analysis. Data are expressed in median (range). No difference was shown in the PLWHA group when compared to the control group in functional capacity (peak oxygen consumption [VO2peak]: 29.9 (20.9–36.4) mL/kg/min vs. 32.2 (24.5–39.4) mL/kg/min) and ventilatory efficiency (oxygen uptake efficiency slope [OUES]: 2,058 [1,474–3,204] vs. 2,612 [1,383–4,119]; minute ventilation carbon dioxide production slope: 27.4 [22.5–33.6] vs. 27.5 [20.4–38.1]). The results are also similar to maximal heart rate, oxygen pulse, gas exchange threshold, respiratory compensation point, heart rate recovery, and half-time of VO2peak recovery. OUES had a strong correlation with VO2peak in the PLWHA group (rs=0.70, P=0.04) and control group (rs=0.78, P=0.02). The results of this study indicate that functional capacity and ventilatory efficiency in PLWHA with well-controlled disease are preserved and are not different from sedentary subjects. In this sense, when CPX is unavailable, the aerobic assessment and prescription could be based on simpler procedures used in healthy subjects.

Cardiorespiratory fitness and muscular strength of deaf futsal players

“…The values found for VT and peak effort were calculated in averages of 40 sec. Respiratory exchange ratio (RER) ≥1.1 was one of the criteria for terminating CPET (Deresz et al, 2018). Relative power was estimated from body weight, and the inclination and speed of the treadmill.…”

Influência do exercício físico no desfecho de infecções virais: revisão bibliográfica de duas décadas de evidências

“…Indivíduos portadores do HIV que são fisicamente menos ativos também apresentam capacidade cardiorrespiratória reduzida (DERESZ et al, 2018). Comparativos realizados entre indivíduos infectados pelo vírus e saudáveis diante de teste em bicicleta ergométrica não apresentaram divergências relacionadas ao VO 2 máximo absoluto, mas os portadores do HIV atingiam a exaustão antes que os indivíduos saudáveis (DIRKSEN et al, 2015).…”

“…Na comparação da capacidade cardiorrespiratória de um grupo HIV+ inativo fisicamente com um grupo saudável igualmente inativo (DERESZ et al, 2018), notou-se que a eficiência respiratória de ambos se assemelha. Frente a um treinamento físico resistido progressivo, há aumento de massa e força muscular e, mesmo pacientes HIV+ que já haviam perdido 10% de seu peso corporal, ainda conseguem responder a estímulos anabólicos (ROUBENOFF; ABAD; LUNDGREN, 2001).…”