Functional biomaterials for comprehensive periodontitis therapy

ROS-scavenging biomaterials for periodontitis

“…148 However, it is difficult to achieve an ideal therapeutic effect by using antioxidative therapy exclusively. 148 As summarized in this review, no matter whether they were the polyphenols, vitamins or proteins mentioned among the organic ROS-scavenging biomaterials, or the metal-based biomaterials as well as carbon-based biomaterials mentioned among the inorganic ROS-scavenging biomaterials, they all showed satisfactory antioxidative properties, but other excellent biological properties, such as hydrophilicity, bioadhesiveness, and photothermal properties also play an important role. Therefore, according to the biological characteristics of different materials, biomaterials could combine with functional molecules which could be used to guide the design of multi-functional biomaterials, and make materials with multiple responses to physical and chemical factors (ROS, temperature and pH), for better therapeutic effects 149,150 (Fig.…”

“…Antioxidant therapy is considered a method of host immunomodulation therapy. 148 However, it is difficult to achieve an ideal therapeutic effect by using antioxidative therapy exclusively. 148 As summarized in this review, no matter whether they were the polyphenols, vitamins or proteins mentioned among the organic ROS-scavenging biomaterials, or the metal-based biomaterials as well as carbon-based biomaterials mentioned among the inorganic ROS-scavenging biomaterials, they all showed satisfactory antioxidative properties, but other excellent biological properties, such as hydrophilicity, bio-adhesiveness, and photothermal properties also play an important role.…”

Advances in hydrogels for the treatment of periodontitis

“…48,49 Many recent studies have shown that bio-functional materials can improve the therapeutic effects of periodontitis. 50 Hydrogels have been extensively investigated as a promising drug delivery system due to their simplicity, biocompatibility, and ability to incorporate both antibacterial and anti-inflammatory agents using various encapsulation methods. [51][52][53] Local administration of hydrogel-based drug formulations around periodontal pockets and lesions has demonstrated potential for precise and sustained delivery of therapeutic agents, thereby aiding in the control of periodontitis progression.…”

Highly transparent antibacterial hydrogel‐polymeric contact lenses doped with silver nanoparticles

“…[12] In particular, both have been exploited in the medical application industry for adhesive coating, films for their attractive properties. [13] Additionally, PVA is water-soluble, where the hydroxyl [ OH] group bonds with alternating carbon atoms. As such, it is categorized as a hydrophilic material.…”