Functional biocompatible nanocomposite films consisting of selenium and zinc oxide nanoparticles embedded in gelatin/cellulose nanofiber matrices

Ahmadi, Azam; Ahmadi, Parisa; Sani, Mahmood Alizadeh; Ehsani, Ali; Ghanbarzadeh, Babak

doi:10.1016/j.ijbiomac.2021.01.135

Cited by 64 publications

(34 citation statements)

References 72 publications

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“…One strategy for achieving this goal is to utilize these agricultural and food waste products to construct innovative packaging materials [ 1 , 2 ]. Various kinds of biopolymers, including polysaccharides (such as cellulose, pectin, chitosan, starch, gums, and their derivatives) and proteins (such as gelatin, casein, whey, and soy proteins) are commonly used as scaffolding materials to assemble biodegradable packaging materials [ 3 , 4 , 5 ]. Nevertheless, the types and amounts of the biopolymers used must be optimized to obtain packaging materials with the required mechanical, barrier, and optical properties [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Smart Biopolymer-Based Nanocomposite Materials Containing pH-Sensing Colorimetric Indicators for Food Freshness Monitoring

et al. 2022

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Nanocomposite biopolymer materials containing colorimetric pH-responsive indicators were prepared from gelatin and chitosan nanofibers. Plant-based extracts from barberry and saffron, which both contained anthocyanins, were used as pH indicators. Incorporation of the anthocyanins into the biopolymer films increased their mechanical, water-barrier, and light-screening properties. Infrared spectroscopy and scanning electron microscopy analysis indicated that a uniform biopolymer matrix was formed, with the anthocyanins distributed evenly throughout them. The anthocyanins in the composite films changed color in response to alterations in pH or ammonia gas levels, which was used to monitor changes in the freshness of packaged fish during storage. The anthocyanins also exhibited antioxidant and antimicrobial activity, which meant that they could also be used to slow down the degradation of the fish. Thus, natural anthocyanins could be used as both freshness indicators and preservatives in biopolymer-based nanocomposite packaging materials. These novel materials may therefore be useful alternatives to synthetic plastics for some food packaging applications, thereby improving the environmental friendliness and sustainability of the food supply.

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Section: Introductionmentioning

confidence: 99%

Smart Biopolymer-Based Nanocomposite Materials Containing pH-Sensing Colorimetric Indicators for Food Freshness Monitoring

et al. 2022

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“…Besides the biochemical properties, their biophysical structure can significantly mediate cell attachment, shape, viability, the differentiation or pluripotency of stem cells, and even tissue repair and regeneration ( Li et al, 2018 ; Cui et al, 2020 ; Yu et al, 2020 ; Yu et al, 2021 ; Zhou et al, 2020 ; Liu et al, 2021 ; Yang et al, 2021a ; Yang et al, 2021b ). Recently, the development of nanofibrous materials has received increasing attention in tissue engineering and regenerative medicine due to their outstanding properties, such as their favorable biological properties, sufficient mechanical strength, highly porous mesh with interconnectivity, extremely high specific surface area, and aspect ratio ( Zhou et al, 2015 ; Zhou et al, 2017 ; Kenry and Lim, 2017 ; Xue et al, 2019 ; Ahmadi et al, 2021 ). In addition, nanofibers can mimic the natural extracellular matrix (ECM) structure in the blood vessel and have been widely used as a blood vessel tissue-engineering scaffold ( Xu et al, 2004 ; Devolder et al, 2011 ).…”

Section: Introductionmentioning

confidence: 99%

Preparation of Fucoidan-Based Electrospun Nanofibers and Their Interaction With Endothelial Cells

Chen

Zhu

Hao

et al. 2021

Front. Bioeng. Biotechnol.

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Sulfated polysaccharide fucoidan (FD) is widely applied in biomedical applications owing to its outstanding bioactivities. In addition to the biochemical features, the architecture of biomaterials plays a critical role in tissue repair and regeneration. Particularly, nanofibers have elicited great interest due to their extracellular matrix-like structure, high specific surface area, and favorable biological properties. Herein, chitosan-modified FD/ultra-high molecular weight polyethylene oxide (UHMWPEO) nanofibers are developed via green electrospinning and electrostatic interaction for studying their interaction with endothelial cells. The appropriate solvent is screened to dissolve FD. The electrospinnability of FD/UHMWPEO aqueous solutions is greatly dependent on the weight ratios of FD/UHMWPEO. The incorporation of UHMWPEO significantly improves the electrospinnability of solution and thermo-stability of nanofibers. Also, it is found that there is good miscibility or no phase separation in FD/UHMWPEO solutions. In vitro biological experiments show that the chitosan-modified FD/UHMWPEO nanofibers greatly facilitate the adhesion of endothelial cells and inhibit the attachment of monocytes. Thus, the designed FD-based nanofibers are promising bio-scaffolds in building tissue-engineered blood vessels.

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“…This might be related to the high porosity and roughness of the PCL/npW scaffold compared to pure PCL. Furthermore, it has been reported that osteoblasts preferentially adhere to the surface as they can provide the necessary structural sites for HAp attachment [ 52 , 53 , 54 ].…”

Section: Discussionmentioning

confidence: 99%

Regeneration of Bone Defects in a Rabbit Femoral Osteonecrosis Model Using 3D-Printed Poly (Epsilon-Caprolactone)/Nanoparticulate Willemite Composite Scaffolds

Bardeei

Seyedjafari

Hossein

et al. 2021

IJMS

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Steroid-associated osteonecrosis (SAON) is a chronic disease that leads to the destruction and collapse of bone near the joint that is subjected to weight bearing, ultimately resulting in a loss of hip and knee function. Zn2+ ions, as an essential trace element, have functional roles in improving the immunophysiological cellular environment, accelerating bone regeneration, and inhibiting biofilm formation. In this study, we reconstruct SAON lesions with a three-dimensional (3D)-a printed composite made of poly (epsilon-caprolactone) (PCL) and nanoparticulate Willemite (npW). Rabbit bone marrow stem cells were used to evaluate the cytocompatibility and osteogenic differentiation capability of the PCL/npW composite scaffolds. The 2-month bone regeneration was assessed by a Micro-computed tomography (micro-CT) scan and the expression of bone regeneration proteins by Western blot. Compared with the neat PCL group, PCL/npW scaffolds exhibited significantly increased cytocompatibility and osteogenic activity. This finding reveals a new concept for the design of a 3D-printed PCL/npW composite-based bone substitute for the early treatment of osteonecrosis defects.

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Functional biocompatible nanocomposite films consisting of selenium and zinc oxide nanoparticles embedded in gelatin/cellulose nanofiber matrices

Cited by 64 publications

References 72 publications

Smart Biopolymer-Based Nanocomposite Materials Containing pH-Sensing Colorimetric Indicators for Food Freshness Monitoring

Smart Biopolymer-Based Nanocomposite Materials Containing pH-Sensing Colorimetric Indicators for Food Freshness Monitoring

Preparation of Fucoidan-Based Electrospun Nanofibers and Their Interaction With Endothelial Cells

Regeneration of Bone Defects in a Rabbit Femoral Osteonecrosis Model Using 3D-Printed Poly (Epsilon-Caprolactone)/Nanoparticulate Willemite Composite Scaffolds

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