Abstract:Uncoupling protein 1 (UCP1) is an essential protein in the mitochondrial inner membrane that mediates non-shivering thermogenesis (NST) and plays an important role in thermoregulation and fat deposition. However, the relationship between the evolution of the UCP1 and fat deposition in the blubber layer in cetaceans remains unclear. Here, frameshift mutations, premature termination, and relaxed selection pressure (ω = 0.9557, p < 0.05) were detected in the UCP1 in cetaceans, suggesting that UCP1 was inac… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.