Functional and Morphological State of the Kidneys in Hypo-and Hyperthyroidism

Abstract

The thyroid gland is one of the most important human organs, since the hormones it produces, in particular triand tetraiodothyronine, are involved in the regulation of many physiological processes, and any dysfunction in the synthesis and secretion of these biologically highly active substances can cause various disorders throughout the body, especially in the processes, which are associated with metabolism and basal metabolism. The effect of iodinecontaining thyroid hormones on kidney function in conditions of their pathology, in particular chronic insufficiency, is currently insufficiently studied. And since the kidneys are aerobic organs and require a significant amount of oxygen for their normal functioning, they become target organs for the action of both excess and lack of thyroid hormones. The information obtained from this article will help expand clinical knowledge, ensure timely diagnosis and conduct the right treatment tactics to increase the life expectancy and survival of patients with chronic kidney disease in hypo-and hyperthyroidism. This review has focused on the studies and findings related to impaired renal function in hypothyroidism and hyperthyroidism. The search for articles, most of which were published in the last 7 years, was carried out in the electronic bibliographic databases e-library, Scopus, Web of Science, Google scholar and PubMed.