“…The synthetic promoter structure utilizing repeats of a known CRE fused with a minimal core promoter is a rational design that usually functions as designed. To date, our colleagues have facilitated in tandem repeats of well-known CREs fused with a short À46 CaMV 35S core promoter to produce biotic and abiotic stress-responsible phytosensors in Arabidopsis, soybean, potato, and poplar (Liu et al, 2014;Persad-Russell et al, 2022;Sears et al, 2023;Sultana et al, 2022;Yang et al, 2021Yang et al, , 2022b. Among these studies, pathogen-and radiation-sensing synthetic promoters were developed from copies of the well-known CREs of the S-box pathogen sensing DNA motif and the DNA recognition motif in the Arabidopsis RAD51 promoter, following the traditional process for synthetic promoter generation (Persad-Russell et al, 2022;Sears et al, 2023).…”