Functional alkoxysilane mediated controlled synthesis of Prussian blue nanoparticles, enabling silica alginate bead development; nanomaterial for selective electrochemical sensing

Synthesis and Applications of Processable Prussian Blue Nanoparticles

“…The finding demonstrated earlier clearly predict the occurrence of uncontrolled nucleation when Prussian blue are made from double precursors unless other wise under specific conditions required to control the nucleation step is adopted [13][14]. Accordingly we demonstrated the role of 4 different organic reagents that enable the controlled conversion [26][27][28][29][30][31] of single precursors into PBNPs; (i) 3-APTMS and cyclohexanone, (ii) tetrahydrofuran hydroperoxide, (iii) tetrahydrofuran and hydrogen peroxide and (iv) tetrahydrofuran hydroperoxide and 2-(3, 4-epoxycyclohexyl) ethyltrimethoxysilane. These reagents precisely control the nucleation of PBNP due to slow dissociation of fraction of single precursors followed by variation in the oxidation state of as generated iron.…”

“…In order to further expand the contribution of these organic reagents we further attempted on simultaneous insertion of both PBNP and noble metal nanoparticles like PdNP within mesoporous silica nanoparticles. Such insertion of both PBNP and metal nanoparticles may allow to introduce several advances not only as vehicle for drug loan and deliver as reported earlier [25] but may allow a specific reaction to take place within mesoporous matrix and as generated reaction intermediate may undergo selective oxidation at electrode surface [30]. Indeed interesting findings on the synthetic insertion of these nanoparticles within mesoporous network of silica nanoparticles (MSNP) has been recorded.…”

“…The typical process of PBNP 4 synthesis as described earlier [30] that involves the mixing of optimum concentration of 2-(3, 4-epoxycyclohexyl) ethyltrimethoxysilane and an aqueous solution of potassium ferricyanide followed by addition of tetrahydrofuran hydroperoxide (THF-HPO) under stirring condition. The resulting green colored solution was allowed to stand in an oven at 60 o C for 3-5 h to yield deep blue PBNP 4 homogeneous suspension and was initially purified by solvent extraction using ethyl acetate.…”

“…Further the efficiency of these organic reducing agent may allow variable rate for the formation of dissociation product of Prussian blue precursor followed by conversion of the oxidation state of Prussian blue component which is key point in yielding pigment with better Prussian blue character. Accordingly we have already demonstrated various organic reagents [26][27][28][29][30][31] to yield PBNPs with further requiring a comparison on the electrochemical activity for further applications.…”

“…Such system may allow to design switchable molecular materials [23] that are attractive for the design of multifunctional innovative devices since their physical properties can be tuned by the application of various external stimuli [24] and reveals that the properties of such material can be tuned to desired application within confined mesoporous matrix as compared to that of in unconfined geometry [23][24][25]. Accordingly, the choice of organic reagent that also allow the confinement of PBNPs within mesoporous matrix along with noble metal nanoparticles may further results into the switchable molecular material of specific applications [26][27][28][29][30][31]. The present article describe the role of 3-amnopropyltrimethoxysilane, cyclohexanone, tetrahydrofuran hydroperoxide that enable the PBNPs formation as homogeneous suspension of PBNPs, hybrid of PBNP and MNP along with enabling the synthetic incorporation of PBNPs and PdNP within mesoporous matrix and reported in this article.…”