Function on Defecation after Surgical Correction in Anorectal Malformations: Results of Krickenbeck Assessment

Background/Aims: Helicobacter pylori (H. pylori) infection highly correlates with erythematous/exudative gastritis, which is one of the endoscopic findings of the Sydney classification system. The present study aimed to evaluate the association between endoscopic severity of erythematous/exudative gastritis and H. pylori infection. Methods: We prospectively enrolled asymptomatic adults who were diagnosed with erythematous/exudative gastritis during screening esophagogastroduodenoscopy. A rapid urease test was performed in all participants to diagnose H. pylori infection. The severity of erythematous/exudative gastritis was determined based on the Sydney classification system. Two investigators independently evaluated the endoscopic findings. The primary endpoint was H. pylori infection rate according to the severity of erythematous/exudative gastritis (mild vs. moderate-to-severe). Results: A total of 177 patients with erythematous/exudative gastritis were included. The rate of H. pylori infection was 86.4% in all patients. Of 177 included patients, 78 were at mild degree, 48 were at moderate degree, and 51 were at severe degree. The inter-observer variation was 4.6% and kappa value was 0.593. H. pylori infection rate was similar between patients with mild erythematous/exudative gastritis and those with moderate-to-severe erythematous/exudative gastritis (91.0% vs. 82.8%, p=0.115). Even after adjusting potential confounding variables, the severity of erythematous/exudative gastritis was not associated with H. pylori infection rate. Conclusions: H. pylori infection is commonly observed in patients with erythematous/exudative gastritis. However, the severity of erythematous/exudative gastritis is not associated with H. pylori infection rate.

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Prediction of Helicobacter pylori Infection by Endoscopic Severity of Erythematous/exudative Gastritis in Asymptomatic Adults

Kim

Rhee

et al. 2022

Korean J Gastroenterol

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Effect of Roux-en-Y Gastric Bypass on Body Weight, Ghrelin and PYY_3-36in Diet-induced Obese Rats

et al. 2010

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Purpose:Obesity is considered an epidemic worldwide. Nonsurgical treatment such as dietary, physical and pharmacological therapies have limited success and thus, bariatric surgery is the ultimate option. Roux-en-Y gastric bypass (RYGB) is a bariatric procedure, which is a restrictive and malabsorptive procedure simultaneously. The purpose of this study was to develop surgical rat models of bariatric surgery and analyze the effect of gastric bypass on body weight, ghrelin and polypeptide YY 3-36 (PYY 3-36 ) changes in rats. Methods: RYGB, sleeve gastrectomy (SG) and sham operation were performed in diet-induced obese rats and compared to obese control and normal control rats. Results: In RYGB group, 20.7±8.56% of weight loss was achieved on postoperative day 18 and maintained thereafter. This outcome was significant compared to SG (8.8±1.82%) and sham operated (6.2±2.45%) groups. When pre-and postoperative ghrelin levels were compared, there was a significant decrease in RYGB group (P＜ 0.028); nonetheless, there was no difference in SG and sham operated groups. When pre-and postoperative PYY 3-36 levels were compared, there was a significant increase in RYGB (P＜0.028), SG (P＜0.031) and sham operated (P＜0.031) groups. Conclusion: We developed surgical rat models of RYGB and SG. Those rats that underwent RYGB lost significant body weight and maintained the weight thereafter. The decrease in ghrelin and increase in PYY 3-36 may be associated with loss of appetite and delay in intestinal transit time with subsequent weight loss maintenance. In the future, this rat model would serve as a tool for further study on endocrine regulation of obesity. (J Korean Surg Soc 2010;79:155-162)

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Clinical Usefulness of Sentinel Lymph Node Biopsy in the Surgical Treatment of Malignant Melanoma

et al. 2010

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Function on Defecation after Surgical Correction in Anorectal Malformations: Results of Krickenbeck Assessment

Abstract: Purpose:The final aim of operation for anorectal malformations (ARMs) is acquisition of normal bowel habit by preserving an anorectal function. This study was performed to assess the functional results after definite correction of the malformations.

Cited by 8 publications

References 27 publications

Prediction of Helicobacter pylori Infection by Endoscopic Severity of Erythematous/exudative Gastritis in Asymptomatic Adults

Prediction of Helicobacter pylori Infection by Endoscopic Severity of Erythematous/exudative Gastritis in Asymptomatic Adults

Effect of Roux-en-Y Gastric Bypass on Body Weight, Ghrelin and PYY_3-36in Diet-induced Obese Rats

Clinical Usefulness of Sentinel Lymph Node Biopsy in the Surgical Treatment of Malignant Melanoma

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Function on Defecation after Surgical Correction in Anorectal Malformations: Results of Krickenbeck Assessment

Abstract: Purpose:The final aim of operation for anorectal malformations (ARMs) is acquisition of normal bowel habit by preserving an anorectal function. This study was performed to assess the functional results after definite correction of the malformations.

Cited by 8 publications

References 27 publications

Prediction of Helicobacter pylori Infection by Endoscopic Severity of Erythematous/exudative Gastritis in Asymptomatic Adults

Prediction of Helicobacter pylori Infection by Endoscopic Severity of Erythematous/exudative Gastritis in Asymptomatic Adults

Effect of Roux-en-Y Gastric Bypass on Body Weight, Ghrelin and PYY3-36in Diet-induced Obese Rats

Clinical Usefulness of Sentinel Lymph Node Biopsy in the Surgical Treatment of Malignant Melanoma

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Resources

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Effect of Roux-en-Y Gastric Bypass on Body Weight, Ghrelin and PYY_3-36in Diet-induced Obese Rats