Abstract:The aim of this study was to investigate the function of human insulin-like growth factor-1 (hIGF-1) transgene in vivo towards the regeneration of peripheral nerves. Thirty (30) male Wistar rats were randomly grouped after the sciatic nerve regeneration chamber model was set up. The hIGF-1 Treatment Group (TG) was injected the mixed solution of pcDNAhIGF-1 and LipfectAmine (hIGF-1 DNA was 4 ug) immediately at the spot of crush injury. The Treatment Model Group (MG) was injected 10 ul of the mixed solution of p… Show more
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