Function and Accuracy of Glucose Sensors Beyond Their Stated Expiry Date

Abstract

Neither the expiry date nor the 3-day period of use limits the reliable function of a CGMS sensor. Sensors were found to function as long as 18 months after the expiry date, mostly for at least 7 days. There were no serious local adverse reactions. Prolongation of shelflife label and insertion time appears to be reasonable. Further studies are in progress.

Benefits of Three-Month Continuous Glucose Monitoring for Persons With Diabetes Using Insulin Pumps and Sensors

“…It is safe and well-tolerated. Its numerical results are comparable with the results of SMPG obtained using glucometers 21,[38][39][40] . The outcome of our study has shown that the clinical effects of CGM are clearly better than those of SMPG: continuous glucose monitoring leads to decrease in HbA1c as early as the end of the first month.…”

“…The sensor is indicated for single use and as a rule works well after a period of seven or more days following introduction 21 . The concentration of glucose in the interstitium (ISFG) correlates highly with P-glucose (PG …”

Occurence of Adverse Events Due to Continuous Glucose Monitoring

“…Since the beginning of the third millenium, CGMS ™ , Medtronic Minimed, Northridge, CA, USA 3 and STS system, Dexcom, San Diego, CA, USA 4,5 , have made CGM, available for thousands of persons with diabetes. The transcutaneous CGMS ™ sensor is labeled to measure the glucose concentration in interstitial fl uid for up to three days after insertion even though it remains stable for a longer period [5][6][7][8][9][10][11] . On the other hand, the potential risks of adverse events due to longer insertion time should be taken into consideration.…”

Glycaemic Index of Selected Foodstuffs in Healthy Persons

“…The CGMS sensor was safe for measuring the plasma glucose in the course of 9 days 23 . The function and accuracy of glucose sensors inserted for more than 3 days was also demonstrated 24 . In our study a total of 640 tests with 11 meals were performed and 491 (77 %) of these were complete and suitable for further evaluation 20 .…”