Abstract:LATE-STAGE FUNCTIONALIZATION OF C—H BONDS IN ORGANIC SYNTHESIS. The development of new strategies for the functionalization of the historically inert C—H bond arises as an excellent way to create new carbon—carbon and carbon— heteroatom bonds. With increasingly chemo- and site-selective methods that enables the late-stage functionalization of C—H bonds, the modification of specific sites in natural products and pharmaceuticals without altering their scaffold emerges as a powerful means for the diversification … Show more
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