Fumigation of Brazil nuts with allyl isothiocyanate to inhibit the growth of <i>Aspergillus parasiticus</i> and aflatoxin production

Lopes, Lucas F.; Bordin, Keliani; Lara, Gabriel H. C. de; Saladino, Federica; Quiles, Juan Manuel; Meca, Giuseppe; Luciano, Fernando Bittencourt

doi:10.1002/jsfa.8527

Cited by 23 publications

(17 citation statements)

References 21 publications

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“…The reactivity of phenols and aldehydes in EOs to proteins and enzymes is the major mechanism, as reported for isothiocyanates. Isothiocyanate were successfully used to inhibit Aspergillus parasiticus in vitro at doses of 5 mg (Manyes et al, 2015) or even in gaseous form in foods at concentrations of 100.01 ml L −1 in wheat flour (Nazareth et al, 2016), at ≥0.05 ml L −1 in corn kernels (Tracz et al, 2017), at 0.5 ml L −1 in corn, barley, and wheat in simulated silo system (Quiles et al, 2019), at 0.0025 ml L −1 in Brazil nuts (Lopes et al, 2018), and at 46,040 and 78,250 mg/kg in the Italian "piadina" (Saladino et al, 2016).…”

Section: Enzyme Inhibitionmentioning

confidence: 99%

Plant Bioactive Compounds in Pre- and Postharvest Management for Aflatoxins Reduction

et al. 2020

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Aflatoxins (AFs) are secondary metabolites produced by Aspergillus spp., known for their hepatotoxic, carcinogenic, and mutagenic activity in humans and animals. AF contamination of staple food commodities is a global concern due to their toxicity and the economic losses they cause. Different strategies have been applied to reduce fungal contamination and AF production. Among them, the use of natural, plant-derived compounds is emerging as a promising strategy to be applied to control both Aspergillus spoilage and AF contamination in food and feed commodities in an integrated pre-and postharvest management. In particular, phenols, aldehydes, and terpenes extracted from medicinal plants, spices, or fruits have been studied in depth. They can be easily extracted, they are generally recognized as safe (GRAS), and they are foodgrade and act through a wide variety of mechanisms. This review investigated the main compounds with antifungal and anti-aflatoxigenic activity, also elucidating their physiological role and the different modes of action and synergies. Plant bioactive compounds are shown to be effective in modulating Aspergillus spp. contamination and AF production both in vitro and in vivo. Therefore, their application in pre-and postharvest management could represent an important tool to control aflatoxigenic fungi and to reduce AF contamination.

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Section: Enzyme Inhibitionmentioning

confidence: 99%

Plant Bioactive Compounds in Pre- and Postharvest Management for Aflatoxins Reduction

et al. 2020

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“…AITC concentration (0.1 to 2.5%) in hummus [20] and in kimchi [36] was organoleptically accepted by the panelists. Lopes, et al [37] also evaluated sensory the AITC concentration (0.5 to 2.5 µL/L) on Brazil peanuts, in which the highest doses (2.5%) of AITC did not change the sensory properties of Brazil peanuts. In this study, we used 20 to 300 mg of ground mustard seeds in 100 mL packaging volume (0.02 to 0.3% w/v) releasing around 1-30 µg/L in the headspace and 3-20 µg/L in the liquid medium, which is a lower concentration than those in the aforementioned literatures, assuming fewer effects of food sensory.…”

Section: Discussionmentioning

confidence: 99%

Packaging Design Using Mustard Seeds as a Natural Antimicrobial: A Study on Inhibition of Pseudomonas fragi in Liquid Medium

Bahmid

Heising

Fogliano

et al. 2020

Foods

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Pseudomonas fragi is the dominant spoilage organism in various foods, especially in spoiled milk, fish, and meats. Its growth can be inhibited by releasing allyl isothiocyanate (AITC) from ground mustard seeds in food packages. This paper aims to investigate the antimicrobial potential of ground mustard seeds against P. fragi growth and the effectiveness of released AITC concentration from mustard seeds on microbial inhibition of the spoilage bacteria growing in the liquid medium. The AITC concentration in the headspace and the liquid medium was measured and the growth of P. fragi in the liquid medium was monitored. Depending on the concentration of AITC, not only growth was inhibited but a reduction of the total count of P. fragi was even observed. The inactivation rate (k) of P. fragi was estimated using first-order inactivation kinetics and the minimum gaseous-released AITC to inactivate P. fragi was determined. Higher AITC concentration in the headspace and liquid medium was observed when using a higher amount of ground mustard seeds and a lower food to headspace ratio. Increasing the amount of ground mustard seeds (>100 mg per 10 mL liquid medium) led to full inactivation of P. fragi in 48 hours. By using an inhibition sigmoid Emax model, the minimum gaseous-released AITC for inactivation of P. fragi in 48 hours was observed around 15 µg/L headspace. These results indicate that inhibition of the spoilage bacteria and extending the shelf life using ground mustard seeds is only possible by applying a careful design of the packaging system.

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“…AITC has well-documented bactericidal, fungicidal, insecticidal, and herbicidal activities and is frequently used as a food preservative (Guo et al, 2017;Lopes et al, 2017Lopes et al, , 2018. It has been introduced to the U.S. market and elsewhere as a biofumigant (Isagro USA, 2015), and others have reported that preplant soil applications with AITC were effective for several pathogens and weeds under warm conditions in sandy soils (Rosskopf et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Multitactic Preplant Soil Fumigation with Allyl Isothiocyanate in Cut Flowers and Strawberry

Hoffmann

Ajwa

Westerdahl

et al. 2020

hortte

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Allyl isothiocyanate (AITC) is a glucosinolate produced in cruciferous plant species. AITC is known to act as a pesticide on microorganisms, insects, and weeds. Synthetic AITC is registered as a biopesticide for agricultural soil treatment use in the United States and elsewhere in the world. Although a potent pesticide, reports on the weed and pathogen control efficacy of synthetic AITC applied as soil disinfectant are highly variable. Due to the low vapor pressure of AITC, questions remain as to whether pest and weed control efficacy can be improved by combining it with other chemicals. The objective of this study was to assess the control efficacy of AITC stand-alone applications vs. applications, in which AITC was combined with the standard-fumigants chloropicrin, 1,3-dichloropicrin, and methyl isothiocyanate. Two shank-applied on-farm field trials were conducted in cut flower [delphinium (Delphinium elatum), ranunculus (Ranunculus asiaticus)] fields, and two drip tape applied field trials in strawberry (Fragaria ×ananassa) fields in California. Weed pressure, weed seed viability, nematode survival, and pathogen survival of Pythium ultimum, fusarium wilt (Fusarium oxysporum), and verticillium wilt (Verticillium dahliae) were assessed. Cumulative yearly yield of marketable fruit was assessed in the strawberry field trials. The results of this study show that the use of AITC as a stand-alone treatment provided no consistent weed or pathogen control efficacy. However, our results also indicate that shank and drip applied multitactic fumigation approaches with AITC can efficiently control soil-borne diseases and weeds. These findings have potential implications, especially in those areas where certain fumigants are restricted due to regulations and/or availability.

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Fumigation of Brazil nuts with allyl isothiocyanate to inhibit the growth of Aspergillus parasiticus and aflatoxin production

Abstract: Gaseous AITC could be used as an alternative to inhibit the growth of A. parasiticus during storage and transport of Brazil nuts. © 2017 Society of Chemical Industry.

Cited by 23 publications

References 21 publications

Plant Bioactive Compounds in Pre- and Postharvest Management for Aflatoxins Reduction

Plant Bioactive Compounds in Pre- and Postharvest Management for Aflatoxins Reduction

Packaging Design Using Mustard Seeds as a Natural Antimicrobial: A Study on Inhibition of Pseudomonas fragi in Liquid Medium

Multitactic Preplant Soil Fumigation with Allyl Isothiocyanate in Cut Flowers and Strawberry

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