Fulminant hepatitis A complicated by Takotsubo syndrome successfully treated with standard volume plasma exchange

Abstract

Fulminant hepatitis A complicated by Takotsubo syndrome A report case of fulminant hepatitis A complicated by severe cardiac dysfunction, was successfully managed with standard volume plasma exchange.

Infections precipitating Takotsubo cardiomyopathy, an uncommon complication of a common infection

“…The outcome following Takotsubo cardiomyopathy is mostly thought to be benign with reversal of cardiac functions being common [3,16]. There has been reports of recurrence of TTC in around 5 to 6% of patients [3,6,17]. Complications like ventricular arrhythmia and cardiogenic shock have been rarely reported [3,18].…”

“…Haemophilus influenzae [20] L. pneumophila [22] Salmonella [22] Escherichia coli [6] Pseudomonas aeruginosa [6] Klebsiella pneumoniae [6] Klebsiella oxytoca [6] Francisella tularensis [23] Aeromonas hydrophila [6] Rickettsia Orientia tsutsugamushi [29] Miscellaneous bacteria Nocardia cyriacigeorgica [24] Acid fast stain Mycobacterium tuberculosis [10] Nontuberculous Mycobacterium [19] Viral Retrovirus HIV (human immunodeficiency virus) [11] DNA virus Cytomegalovirus [6] Hepatitis C [25] Parvovirus B19 [26] Herpes virus [6] Varicella zoster [7] RNA virus Influenza A * Influenza B [9] Dengue virus [8] Enterovirus [27] Hepatitis A [17] Norovirus [16] SARS-CoV-2 (COVID-19) [12] Fungal Candida glabrata [6] Cryptococcus neoformans [28] Parasites Protozoa Babesia [6] Helminth Paragonimiasis westermani [12] Taenia solium [6]…”

The changing face of hepatology

“…Caballol et al, 21 report on a case of hepatitis A virus-related fulminant hepatic failure complicated by Takotsubo syndrome, where standard volume plasma exchange was successfully used as a salvage therapy to initiate rapid liver and cardiac recovery. This case suggests that standard and not only high-volume plasma exchange can be an effective therapy for patients with fulminant hepatic failure and potential contraindications for liver transplantation.…”