Fulminant group B Streptococcal necrotizing fasciitis in a patient with undiagnosed malignancy: a case report

Streptococcus agalactiae-Induced Soft Tissue Infection in a Nonpregnant Adult After a Gynecological Procedure

“…The incidence of S. agalactiae associated with NF is increasing in nonpregnant adults [ 1 , 3 , 8 , 9 ]. This has been linked mostly with the increase in prevalence of chronic diseases, particularly diabetes and malignancy rather than increased virulence of S. agalactiae [ 9 , 11 ]. The lower extremities, trunk, and peri-anal region are commonly affected [ 1 ], whereas involvement of the neck has been rarely described.…”

“…Streptococcus agalactiae has also been isolated from the skin [ 8 ] and has been implicated as the cause of NF of the foot via contiguous spread in a T1DM patient with a foot ulcer [ 9 ]. The same patient experienced NF of the contralateral foot within a week, due to hematogenous spread as the other foot had no ulcer; blood and tissue cultures for S. agalactiae were positive [ 9 ]. The hematogenous dissemination of S. agalactiae could possibly cause the time lag between first symptoms and presentation of NF in distant fascia and sub-cutaneous tissues [ 9 ].…”

“…The same patient experienced NF of the contralateral foot within a week, due to hematogenous spread as the other foot had no ulcer; blood and tissue cultures for S. agalactiae were positive [ 9 ]. The hematogenous dissemination of S. agalactiae could possibly cause the time lag between first symptoms and presentation of NF in distant fascia and sub-cutaneous tissues [ 9 ].…”