Full Wave 3D Inverse Scattering Transmission Ultrasound Tomography: Breast and Whole Body Imaging

Wiskin, James; Malik, Bilal; Natesan, Rajni; Borup, D.T.; Pirshafiey, Nasser; Lenox, M.; Klock, John C.

doi:10.1109/ultsym.2019.8925778

Cited by 17 publications

(14 citation statements)

References 21 publications

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“…With the rapid development of 3D breast ultrasound imaging device, ultrasound array with thousands of elements has been fabricated recently. 36 Another advantage for XACT to be an in vivo dosimetry is its potential to be combined with anatomical ultrasound imaging. The B-mode ultrasound images and the radiation-induced signals can be obtained by the same transducer.…”

Section: Discussionmentioning

confidence: 99%

“…The physical radius of the 3D hemispherical transducer array is 7.2 cm, and each sensor has an area of 5.71 mm 2 to receive the acoustic signal. With the rapid development of 3D breast ultrasound imaging device, ultrasound array with thousands of elements has been fabricated recently 36 . Another advantage for XACT to be an in vivo dosimetry is its potential to be combined with anatomical ultrasound imaging.…”

Section: Discussionmentioning

confidence: 99%

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X‐ray‐induced acoustic computed tomography for guiding prone stereotactic partial breast irradiation: a simulation study

et al. 2020

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The aim of this study is to investigate the feasibility of x-ray-induced acoustic computed tomography (XACT) as an image guidance tool for tracking x-ray beam location and monitoring radiation dose delivered to the patient during stereotactic partial breast irradiation (SPBI). Methods: An in-house simulation workflow was developed to assess the ability of XACT to act as an in vivo dosimetry tool for SPBI. To evaluate this simulation workflow, a three-dimensional (3D) digital breast phantom was created by a series of two-dimensional (2D) breast CT slices from a patient. Three different tissue types (skin, adipose tissue, and glandular tissue) were segmented and the postlumpectomy seroma was simulated inside the digital breast phantom. A treatment plan was made with three beam angles to deliver radiation dose to the seroma in breast to simulate SPBI. The three beam angles for 2D simulations were 17°, 90°and 159°(couch angles were 0 degrees) while the angles were 90 degrees (couch angles were 0°, 27°, 90°) in 3D simulation. A multi-step simulation platform capable of modelling XACT was developed. First, the dose distribution was converted to an initial pressure distribution. The propagation of this pressure disturbance in the form of induced acoustic waves was then modeled using the k-wave MATLAB toolbox. The waves were then detected by a hemispherical-shaped ultrasound transducer array (6320 transducer locations distributed on the surface of the breast). Finally, the time-varying pressure signals detected at each transducer location were used to reconstruct an image of the initial pressure distribution using a 3D time-reversal reconstruction algorithm. Finally, the reconstructed XACT images of the radiation beams were overlaid onto the structure breast CT. Results: It was found that XACT was able to reconstruct the dose distribution of SPBI in 3D. In the reconstructed 3D volumetric dose distribution, the average doses in the GTV (Gross Target Volume) and PTV (Planning Target Volume) were 86.15% and 80.89%, respectively. When compared to the treatment plan, the XACT reconstructed dose distribution in the GTV and PTV had a RMSE (root mean square error) of 2.408 % and 2.299 % over all pixels. The 3D breast XACT imaging reconstruction with time-reversal reconstruction algorithm can be finished within several minutes. Conclusions: This work explores the feasibility of using the novel imaging modality of XACT as an in vivo dosimeter for SPBI radiotherapy. It shows that XACT imaging can provide the x-ray beam location and dose information in deep tissue during the treatment in real time in 3D. This study lays the groundwork for a variety of future studies related to the use of XACT as a dosimeter at different cancer sites.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

X‐ray‐induced acoustic computed tomography for guiding prone stereotactic partial breast irradiation: a simulation study

et al. 2020

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“…In 2017, another breast ultrasound tomograph system using a combination probe of a pair of 2D array probes and three linear probes was built in QT Ultrasound, LLC, CA, USA and was issued by FDA a 510K alliance. Because they used both low and high frequency signals, a high quality sound speed image can be reconstructed [3].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound computed tomography imaging technique advances in HUST

Ding,

Zhou,

Zhang

et al. 2024

Medical Imaging 2024: Ultrasonic Imaging and Tomography

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Ultrasound computed tomography (UCT) is a new revolution imaging technique in clinic, which was first proposed by Greenleaf from Mayo Clinic in 1980's, and become active in recent 10 years. In this study, we present our research advances in UCT, both techniques and clinic applications. First, an ultrasound computed tomography imaging technique to solve the small breast problem is introduced, which a set of moldings made of solid gel coupling agent (SGCA) are designed for shaping the small breast in UCT, such that a high quality and complete breast can be acquired; secondly, a new UCT technique based on sparse representation and AI technology is developed, which can greatly speed up the imaging speed in UCT by sparsely emission instead of full complete emission; finally many clinic application examples are described to demonstrate the possible potential application in clinic. Furthermore, the future works in UCT in HUST are given.

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“…While waveform inversion is the clinical in vivo gold standard for obtaining high-resolution diagnostic-quality images of the speed of sound in tissue, 11,12 it remains unclear to what extent the starting model for the sound speed profile in the medium impacts the solution of waveform inversion. In a ring array geometry, a refractioncorrected bent ray tomography is often used in ultrasound tomography to obtain a starting model prior to waveform inversion.…”

Section: Introductionmentioning

confidence: 99%

Impact of starting model on waveform inversion in ultrasound tomography

Ali

Mitcham

Duric

2023

Medical Imaging 2023: Ultrasonic Imaging and Tomography

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The convergence of waveform inversion in ultrasound tomography is heavily impacted by the choice of starting model. Ray tomography is often used as the starting model for waveform inversion; however, artifacts resulting from ray tomography can continue to persist during waveform inversion. On the other hand, a homogeneous starting model for waveform inversion may result in cycle skipping artifacts if the frequency of the transmitted waveform is too high or the error between the starting model and ground-truth is too large. Clinical in vivo breast data suggests that waveform inversion from a homogeneous starting model is sufficient for an accurate reconstruction of the speed of sound if the starting model is close enough to the average speed of sound in the medium and the starting frequency for waveform inversion is sufficiently low to avoid cycle skipping. Comparing the results of waveform inversion using ray tomography and a homogeneous sound speed as initial models, the homogeneous starting model avoids oscillatory artifacts produced by ray tomography at the edges of the breast. Although the RMS error between the two waveform inversion results is 29.6 m/s, most of the error is the result of reconstruction artifacts at the edges of the breast. When the RMS error is measured inside the breast away from its boundaries, this RMS error drops down to 11.5 m/s.

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Full Wave 3D Inverse Scattering Transmission Ultrasound Tomography: Breast and Whole Body Imaging

Cited by 17 publications

References 21 publications

X‐ray‐induced acoustic computed tomography for guiding prone stereotactic partial breast irradiation: a simulation study

X‐ray‐induced acoustic computed tomography for guiding prone stereotactic partial breast irradiation: a simulation study

Ultrasound computed tomography imaging technique advances in HUST

Impact of starting model on waveform inversion in ultrasound tomography

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