Full resolution of subacute acetabular osteomyelitis in an 11-year-old patient following nonsurgical management

Kerr, Barry D; Finlayson, Graham D.; Thompson, Lara J; McConway, J.

doi:10.4103/0975-7341.207174

Cited by 1 publication

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…co-amoxiclav, can be safely used in many types of bone and joint infections, including for diabetic foot OM (11). In the United Kingdom, the prescribing of oral FLU has increased by 21% during the past decade (12), and oral FLU can be used for OM (13). Considering the potential benefits, and lack of published data, we present this narrative review to address the potential place of oral FLU for treating OM.…”

Section: Ivyspringmentioning

confidence: 99%

Oral Flucloxacillin for Treating Osteomyelitis: A Narrative Review of Clinical Practice

Preiss

Kriechling

Montrasio

et al. 2020

J. Bone Joint Infect.

View full text Add to dashboard Cite

Abstract. Flucloxacillin (FLU) administered by the oral route is widely used for treating various infections, but there are no published retrospective or prospective trials of its efficacy, or its advantages or disadvantages compared to parenteral treatment or other antibiotics for treating osteomyelitis. Based on published in vitro data and expert opinions, other non-β-lactam oral antibiotics that have better bone penetration are generally preferred over oral FLU. We reviewed the literature for studies of oral FLU as therapy of osteomyelitis (OM), stratified by acute versus chronic and pediatric versus adult cases. In striking contrast to the prevailing opinions and the few descriptive data available, we found that treatment of OM with oral FLU does not appear to be associated with more clinical failures compared to other oral antibiotic agents. Because of its narrow antibiotic spectrum, infrequent severe adverse effects, and low cost, oral FLU is widely used in clinical practice. We therefore call for investigators to conduct prospective trials investigating the effectiveness and potential advantages of oral FLU for treating OM.

show abstract

Section: Ivyspringmentioning

confidence: 99%