Full Resistance and Decreased Susceptibility to Carbapenems in IMP-13-Producing Pseudomonas aeruginosa Isolates from an Outbreak

Panel strain ofKlebsiella pneumoniaefor beta-lactam antibiotic evaluation: their phenotypic and genotypic characterization

“…Even though IMP-1 enzyme is known to hydrolyze piperacillin and tazobactam, this strain appeared susceptible. Similar cases have been reported earlier (Chen et al, 2009; Koh, Wang & Sng, 2004; Mushtaq, Ge & Livermore, 2004; Picao et al, 2013; Santella et al, 2010; Scheffer et al, 2010), which may be due to inherent susceptibility to the particular antibiotics. Other resistances are conferred due to the presence of 3 copies of bla TEM-1 and bla SHV-11 .…”

Intercontinental Dissemination of IMP-13-Producing Pseudomonas aeruginosa Belonging in Sequence Type 621

“…IMP-13-producing P. aeruginosa isolates have also been detected in Argentina, where IMP-13 and IMP-16 represent the only IMP-type MBLs thus far reported (1,4,15). In this work, we investigated 20 IMP-13-producing P. aeruginosa isolates (19 clinical isolates and 1 environmental isolate) from an outbreak in Argentina (15) and compared them with P. aeruginosa AV65, as a representative of the IMP-13-producing clone spreading in Italy (13).…”

Spread of Clonally Related Escherichia coli Strains Harboring an IncA/C 1 Plasmid Encoding IMP-8 and Its Recruitment into an Unrelated MCR-1-Containing Isolate

“…IMP-type metallo-␤-lactamases (MBLs) were first identified in the early 1990s in Pseudomonas aeruginosa in Japan and since then have been globally reported, mostly in P. aeruginosa and in other nonfermenting Gram-negative bacilli (1). Studies performed in Argentina reported the presence of IMP-13 in P. aeruginosa and IMP-8 in Enterobacter cloacae (2)(3)(4). IMP-8 was initially described in Klebsiella pneumoniae in Taiwan, where it became the dominant MBL among Enterobacteriaceae (5).…”