Full-mouth ultrasonic debridement associated with povidone iodine rinsing in GAgP treatment: a randomised clinical trial

Vale, Hugo Felipe do; Casarin, Renato Corrêa Viana; Taiete, Tiago; Ambrosano, Gláucia María Bovi; Silvério, Karina Gonzáles; Nociti, Francisco Humberto; Sallum, Enílson Antônio; Casati, Márcio Zaffalon

doi:10.1007/s00784-015-1471-y

Cited by 15 publications

(14 citation statements)

References 44 publications

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“…AgP and CP patients were identified on the basis of 1999 International Workshop for the Classification of Periodontal Diseases and Conditions . Most of AgP patients were treated in previous studies or in one of the three Graduate Clinics. Further, these patients needed at the first examination the presence of at least 20 teeth, at least 8 teeth with a PD ≥ 5 mm with bleeding on probing (having at least 2 with PPD ≥ 7 mm), < 35 years of age for AgP patients, and > 35 years for CP.…”

Section: Methodsmentioning

confidence: 99%

Validation of reported GLT6D1 (rs1537415), IL10 (rs6667202), and ANRIL (rs1333048) single nucleotide polymorphisms for aggressive periodontitis in a Brazilian population

Taiete

Casati

Stolf

et al. 2018

Journal of Periodontology

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Section: Methodsmentioning

confidence: 99%

Validation of reported GLT6D1 (rs1537415), IL10 (rs6667202), and ANRIL (rs1333048) single nucleotide polymorphisms for aggressive periodontitis in a Brazilian population

Taiete

Casati

Stolf

et al. 2018

Journal of Periodontology

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“…Three studies were multi-arm trials [ 48 , 52 , 53 ]. The adjuncts included were: (1) antimicrobial photodynamic therapy (aPDT) indocyanine green (ICG) [ 54 , 55 ], (2) aPDT methylene blue (MB) 0.005% [ 56 , 57 ], (3) aPDT MB 1% [ 47 , 58 , 59 , 60 ], (4) aPDT phenothiazine chloride (PC) [ 61 , 62 ], (5) aPDT toluidine blue O (TBO) [ 53 ], (6) chlorhexidine (CHX) chip [ 52 , 63 , 64 ], (7) CHX xanthan gel [ 65 , 66 ], (8) doxycycline hyclate (DH) gel [ 50 , 67 ], (9) metronidazole (MET) gel [ 68 , 69 ], (10) minocycline (MINO) gel [ 49 , 70 ], (11) MINO microspheres [ 48 , 71 , 72 ], (12) povidone iodine (PI) 10% irrigating solution [ 73 ], (13) sulfonic/sulfuric acid (SA) gel [ 51 ], and (14) tetracycline (TC) fibers [ 52 ]. SMD alone was used as the reference comparator arm.…”

Section: Resultsmentioning

confidence: 99%

Clinical Efficacy of Single Application Local Drug Delivery and Adjunctive Agents in Nonsurgical Periodontal Therapy: A Systematic Review and Network Meta-Analysis

2020

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This review aimed to rank the clinical efficacy of commercially available single-application local drug delivery and adjunctive agents (LDAs) compared with subgingival mechanical debridement (SMD) in nonsurgical periodontal therapy (NSPT). Randomized controlled clinical trials that compared LDAs against SMD alone or with placebo in adults (aged at least 18 years) diagnosed with periodontitis with a minimum of 6 months follow-up were included. A frequentist approach to random-effects network meta-analysis was implemented. The efficacies of the LDAs measured by probing pocket depth (PPD) reduction and clinical attachment level (CAL) gain were reported as mean difference (MD) with 95% confidence intervals (CIs). The treatments were ranked according to their P-score. Four network meta-analyses suggested that sulfonic/sulfuric acid gel (PPD MD −1.13 mm, 95% CI −1.74 to −0.53, P-score 0.91; CAL MD −1.09 mm, 95% CI −1.58 to −0.61, P-score 0.95) and doxycycline hyclate gel (PPD MD −0.90 mm, 95% CI −1.50 to −0.30, P-score 0.93; CAL MD −0.84 mm, 95% CI −1.40 to −0.28, P-score 0.92) were the most effective in reducing PPD and gaining CAL in split-mouth and parallel studies, respectively (moderate certainty of evidence). LDAs have differing efficacies, but they present with possible clinical significance over SMD alone in NSPT.

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“…, do Vale et al. ) and screened to confirm eligibility. The manual searching of the reference lists of the selected papers provided two additional suitable publications (Rosling et al.…”

Section: Resultsmentioning

confidence: 99%

The effect on clinical parameters of periodontal inflammation following non‐surgical periodontal therapy with ultrasonics and chemotherapeutic cooling solutions: a systematic review

Sluijs

Weijden

et al. 2016

J Clinic Periodontology

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The collective evidence indicates that overall, no additional effects were observed. There is a "very weak" recommendation based on the sub-analysis showing that in conjunction with PVP, a very small gain in CAL may be expected. For the use of CHX or EO, the added effect can be considered to be "zero." Therefore, the strength and direction of the recommendation emerging from this review is against their use.

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Full-mouth ultrasonic debridement associated with povidone iodine rinsing in GAgP treatment: a randomised clinical trial

Abstract: The FMUD is a valid option for the treatment of GAgP, but the use of 10 % PVPI did not improve the results of the periodontal therapy.

Cited by 15 publications

References 44 publications

Validation of reported GLT6D1 (rs1537415), IL10 (rs6667202), and ANRIL (rs1333048) single nucleotide polymorphisms for aggressive periodontitis in a Brazilian population

Validation of reported GLT6D1 (rs1537415), IL10 (rs6667202), and ANRIL (rs1333048) single nucleotide polymorphisms for aggressive periodontitis in a Brazilian population

Clinical Efficacy of Single Application Local Drug Delivery and Adjunctive Agents in Nonsurgical Periodontal Therapy: A Systematic Review and Network Meta-Analysis

The effect on clinical parameters of periodontal inflammation following non‐surgical periodontal therapy with ultrasonics and chemotherapeutic cooling solutions: a systematic review

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