Full Macular Translocation for Choroidal Neovascularization in the Era of Intravitreal Pharmacological Therapy

Haverbeke, Greg M; Claes, C

doi:10.1097/iae.0b013e3181f57d3d

Cited by 3 publications

(3 citation statements)

References 33 publications

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“…64 In addition, some patients may develop complications related to anti-VEGF therapy, such as rips in the pigment epithelium at an estimated incidence rate of 0.8%. 65 Surgery may be a viable option for those who fail or stop responding to pharmacologic therapy, an approach still yet to be proven successful. While the current treatment of choice for neovascular macular degeneration remains intravitreal anti-angiogenic therapy, even in today's environment some patients may still benefit from surgical treatment, especially those with thick macular hemorrhage, and perhaps even those with non-responsiveness or complications related to anti-VEGF treatment.…”

Section: Resultsmentioning

confidence: 99%

Surgical Treatment of Age-Related Macular Degeneration

Skaf

Mahmoud

2011

Seminars in Ophthalmology

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Choroidal neovascularization (CNV) and geographic atrophy (GA) are serious and potentially devastating complications of age-related macular degeneration (AMD), a leading cause of blindness in the developed world. While anti-vascular endothelial growth factor (VEGF) therapies have emerged as the current standard treatment of choice for choroidal neovascularization, the requirement for indefinite injections places a tremendous burden on physicians and patients, and may have disappointing outcomes in hemorrhagic neovascular AMD. No superior agents exist to treat large subretinal hemorrhage and geographic atrophy. Over the years, several vitreoretinal surgical approaches have been developed to treat macular degeneration, and these surgical options may still play a role in the management of specific complications of AMD. This review summarizes the principles, techniques, and results of surgical treatments for neovascular and non-neovascular age-related macular degeneration, with emphasis on submacular surgery for removal of CNV, full and limited macular translocation, retinal pigment epithelium, and choroid transplants as well as treatment of thick subretinal hemorrhage.

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Section: Resultsmentioning

confidence: 99%

Surgical Treatment of Age-Related Macular Degeneration

Skaf

Mahmoud

2011

Seminars in Ophthalmology

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“…Moreover, most complications such as retinal detachments, macular holes and choroidal haemorrhages were so severe that serious visual loss was inevitable. Nonetheless, patients who have been refractory to anti-VEGF therapy would be suitable candidates22 for FMT, which should, however, only be an option for selected cases.…”

Section: Discussionmentioning

confidence: 99%

Consecutive case series with long-term follow-up of full macular translocation for myopic choroidal neovascularisation

et al. 2014

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“…8,18 MTS360 has been shown to have better improvement in near visual acuity when compared to PDT (+7 letters versus −9.6 letters). 54,55 8,18,40,57 The impact of MTS360 on other visual functions, including reading speed, contrast sensitivity, and color vision, have also been reported.…”

Section: Extraocular Muscle Surgery Following Macular Translocationmentioning

confidence: 99%