Full-Length Genome Sequence of Porcine Epidemic Diarrhea Virus Strain CH/GX/2015/750A

Abstract

We report here the complete genome sequence of porcine epidemic diarrhea virus (PEDV) strain CH/GX/2015/750A (750A), which was isolated from a suckling piglet with watery diarrhea in Guangxi, China. The isolate is genetically close to other recent Chinese variant PEDVs and distinct from the classical PEDVs.

Complete Genome Sequence of a Porcine Epidemic Diarrhea Virus Isolated in Belgorod, Russia, in 2008

“…The genomic organization of the isolate is similar to the canonical PEDV structure described elsewhere (6, 7). The most similar PEDV sequences at the whole-genome level were among Chinese PEDV isolates (i.e., KX791060, KC210147, KC210145, and KT021229) with 97% identity and an E value of 0.0.…”

A Genetically Engineered Bivalent Vaccine Coexpressing a Molecular Adjuvant against Classical Swine Fever and Porcine Epidemic Diarrhea

“…In this study, the GX750A strain, which belongs to the GII-a subgroup, was utilized. The S protein of GX750A strain exhibits two insertion regions ( 59 QGVN 62 and 140 N) and one deletion region ( 161 GK 162 ) within the N-terminal region, distinguishing it from the classical GI strain [44]. These insertion and deletion mutations caused variability in viral genome and may enhance pathogenicity and antigenicity in PEDV GII variants [45].…”

“…Oral and rectal swabs, as well as fecal samples, were collected for viral detection. The CSF and PED clinical scores were determined according to previously described methods (42,43,44). EDTA-treated blood and serum were sampled from the experimental pigs at 0, 7, 14, 21, and 28 dpv and 0, 3, 7, 14, and 21 dpc.…”