Full-field sensitivity threshold and the relation to the oxygen metabolic retinal function in retinitis pigmentosa

Zabek, Olga; Calzetti, Giacomo; Prétot, Dominique; Scholl, Hendrik P. N.; Waizel, Maria della Volpe

doi:10.1007/s00417-022-05638-1

Cited by 2 publications

(8 citation statements)

References 43 publications

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“…Other colours such as green (513 nm) have been used rarely [ 49 ]. A white stimulus is produced by using a broadband white light with a colour temperature of 6500 K [ 29 , 31 , 36 ]. Short wavelength (blue) and long wavelength (including red) stimuli can be produced using a range of LEDs [ 1 , 2 , 5 , 27 , 30 , 34 , 35 , 50 ].…”

Section: Technical Considerationsmentioning

confidence: 99%

“…Widely different periods of adaptation have been used, ranging from no adaptation to 2 h, [ 1 , 2 , 26 , 27 , 29 – 32 , 34 , 36 – 40 , 47 , 48 , 50 ] with a median time of approximately 45 min for dark-adapted testing. In disorders characterised by predominant rod dysfunction where dark adaptation may be impaired or delayed, a longer fixed period of dark adaptation may be needed to enable measurement of maximum sensitivity [ 53 ].…”

Section: Technical Considerationsmentioning

confidence: 99%

“…The use of auditory signals to enhance responses to psychophysical testing has been reported in the perimetry literature [ 54 , 55 ]. During FST, an auditory prompt signals to the subject when they should respond “yes” (seen) or “no” (not seen) for two button testing paradigm [ 5 , 24 , 26 , 27 , 29 , 31 , 33 , 34 , 36 , 41 – 43 ]. An auditory signal is generally not relevant for one button testing paradigm [ 32 ].…”

Section: Technical Considerationsmentioning

confidence: 99%

“…However, it is important to avoid extended test sessions that may affect results due to subject fatigue. The majority of studies reviewed took an average of 3 measurements [ 5 , 26 , 27 , 29 , 36 , 44 – 46 , 50 ].…”

Section: Technical Considerationsmentioning

confidence: 99%

“…The most commonly used function for the FST is the two-parameter modified Weibull fit, estimating the stimulus strength associated with 50% probability of detection based on staircase responses (Fig. 1 ) [ 5 , 26 – 30 , 33 , 34 , 36 – 40 , 44 – 48 , 50 ]. The equation of the Weibull function utilised is specified below, though all details of the modifications are not in the public domain and remain proprietary.…”

Section: Technical Considerationsmentioning

confidence: 99%

See 4 more Smart Citations

ISCEV and IPS guideline for the full-field stimulus test (FST)

Jolly,

Grigg,

McKendrick

et al. 2024

Doc Ophthalmol

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The full-field stimulus test (FST) is a psychophysical technique designed for the measurement of visual function in low vision. The method involves the use of a ganzfeld stimulator, as used in routine full-field electroretinography, to deliver full-field flashes of light. This guideline was developed jointly by the International Society for Clinical Electrophysiology of Vision (ISCEV) and Imaging and Perimetry Society (IPS) in order to provide technical information, promote consistency of testing and reporting, and encourage convergence of methods for FST. It is intended to aid practitioners and guide the formulation of FST protocols, with a view to future standardisation.

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Section: Technical Considerationsmentioning

confidence: 99%

Section: Technical Considerationsmentioning

confidence: 99%

Section: Technical Considerationsmentioning

confidence: 99%

Section: Technical Considerationsmentioning

confidence: 99%

Section: Technical Considerationsmentioning

confidence: 99%

See 3 more Smart Citations

ISCEV and IPS guideline for the full-field stimulus test (FST)

Jolly,

Grigg,

McKendrick

et al. 2024

Doc Ophthalmol

View full text Add to dashboard Cite

show abstract

Full-field stimulus threshold testing: a scoping review of current practice

Shi

Hall

Thompson

2023

Eye

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The full-field stimulus threshold (FST) is a psychophysical measure of whole-field retinal light sensitivity. It can assess residual visual function in patients with severe retinal disease and is increasingly being adopted as an endpoint in clinical trials. FST applications in routine ophthalmology clinics are also growing, but as yet there is no formalised standard guidance for measuring FST. This scoping review explored current variability in FST conduct and reporting, with an aim to inform further evidence synthesis and consensus guidance. A comprehensive electronic search and review of the literature was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis Extension for Scoping Reviews (PRISMA-ScR) checklist. Key source, participant, methodology and outcomes data from 85 included sources were qualitatively and quantitatively compared and summarised. Data from 85 sources highlight how the variability and insufficient reporting of FST methodology, including parameters such as units of flash luminance, colour, duration, test strategy and dark adaptation, can hinder comparison and interpretation of clinical significance across centres. The review also highlights an unmet need for paediatric-specific considerations for test optimisation. Further evidence synthesis, empirical research or structured panel consultation may be required to establish coherent standardised guidance on FST methodology and context or condition dependent modifications. Consistent reporting of core elements, most crucially the flash luminance equivalence to 0 dB reference level is a first step. The development of criteria for quality assurance, calibration and age-appropriate reference data generation may further strengthen rigour of measurement.

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Full-field sensitivity threshold and the relation to the oxygen metabolic retinal function in retinitis pigmentosa

Cited by 2 publications

References 43 publications

ISCEV and IPS guideline for the full-field stimulus test (FST)

ISCEV and IPS guideline for the full-field stimulus test (FST)

Full-field stimulus threshold testing: a scoping review of current practice

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