Full-field optical coherence tomography by two-dimensional heterodyne detection with a pair of CCD cameras

Abstract

A two-dimensional heterodyne detection technique based on the frequency-synchronous detection method [Jpn. J. Appl. Phys. 39, 1194 (2000)] is demonstrated for full-field optical coherence tomography. This technique, which employs a pair of CCD cameras to detect the in-phase and quadrature components of the heterodyne signal simultaneously, offers the advantage of phase-drift suppression in interferometric measurement. Horizontal cross-sectional images are acquired at the rate of 100 frames/s in a single longitudinal scan, with a depth interval of 6 microm, making the rapid reconstruction of three-dimensional images possible.

Fourier spectrum analysis of full-field optical coherence tomography for tissue imaging

“…In fact, this en face imaging ability is one advantage of FFOCT over other OCT techniques. En face images are helpful in the cases where a horizontal cross-sectional image is needed [5] or the transverse distribution of biological structures has to be examined [11]. The en face view may also supply new information which may complement that provided by the depth view [49].…”

“…In FFOCT, en face images were produced without any transverse scanning. In initial efforts, an infrared light-emitting diode (LED) was used for illuminating a Linnik interference microscope [2][3][4][5]. A thermal light source was then used for illumination [6][7][8][9][10][11].…”

Selected Methods of Image Analysis in Optical Coherence Tomography

“…The ACM method -active modified contour, it is based on basic information acquired from image like for example the plainest RPE layer which will be identified in the first period and on its base the analysis of the remaining layers like OPL or IS/OS will be carried out (Akiba et al, 2003;Choma el at., 2003). The picture 3 presents structure of unit algorithm (block scheme) in which chosen blocks (layer analysis OPL, IS/OS, ELM ) can work independently.…”

Large Area Full-Field Optical Coherence Tomography and its Applications

“…The scanning depth is determined by the difference of two distances U and V. Fig. (1d) is a system configuration with a pair of CCD cameras, which make system capable of grabbing images with a phase-deference [12]. Two liquid crystal shutters are used to introduce /2 phase shift between images grabbed by two CCD cameras, as described by Eq.…”

“…These parallel OCT systems are usually called fullfield OCT (FF-OCT) systems. A few OCT systems working directly on 2D full-field images were reported [10][11][12][13]. As the fibre output aperture is about a micron leveling size, the *Address correspondence to this author at the Optics Group, Institute for Microstructural Sciences, National Research Council Canada, 1200 Montreal Road, Ottawa, K1A 0R6, Canada; E-mail: Shoude.Chang@nrc-cnrc.gc.ca working area of FB-OCT system is normally about hundreds of squared microns.…”