Full‐face photorejuvenation of photodamaged skin by intense pulsed light with integrated contact cooling: Initial experiences in Asian patients

Negishi, Kei; Wakamatsu, Shingo; Kushikata, Nobuharu; Tezuka, Yukiko; Kotani, Yasuyo; Shiba, Kyouko

doi:10.1002/lsm.10036

Cited by 126 publications

(100 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…IPL patients reported more pain and as this is a patient-reported outcome and patients were not blinded to intervention we cannot tell if this pain was real or perceived [19][20][21]. However, pain of mild to moderate intensities related to IPL is a known adverse effect [23][24][25]. The IPLsystem used in this trial did not use cooling of the epidermis, which is utilized in newer IPL-systems to minimize treatment-related pain [22][23][24][25].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Paring and intense pulsed light versus paring alone for recalcitrant hand and foot warts: A randomized clinical trial with blinded outcome evaluation

Togsverd‐Bo¹,

Gluud²,

Winkel³

et al. 2010

Lasers Surg Med

View full text Add to dashboard Cite

Background and Objectives: Treatment of recalcitrant viral warts remains a therapeutic challenge. Intense pulsed light (IPL) has been suggested effective to clear wart tissue. The objective was in a randomized controlled trial to assess the efficacy of paring followed by IPL versus paring alone for recalcitrant hand and foot warts. Materials and Methods: Eighty-nine patients with recalcitrant hand and foot warts were included and randomized (1:1) to three treatments at 3-week intervals with either paring of warts followed by IPL or paring of warts alone. IPL was given with the Ellipse Flex IPL system (Danish Dermatologic Development A/S, Hørsholm, Denmark, 400-950 nm, 5.5 millisecond pulse duration in double pulses with a 2 millisecond interval, 26.0-32.5 J/ cm 2 repetitive passes). The primary outcome was complete and partial clearance of warts evaluated by blinded photo assessment at 6 weeks after final treatment. Secondary outcomes were treatment related pain and adverse reactions. Results: We found no significant difference in clearance of warts between the two intervention groups (OR 1.64, 95% confidence interval 0.62-4.38). Paring followed by IPL resulted in complete or partial clearance of wart tissue in nine (22%) and five patients (12.2%) versus five (13.5%) and four patients (10.8%) from paring alone. Mostly plantar warts were treated (92.1%). The pain intensity after paring and IPL was moderate and significantly higher than the pain intensity after paring alone (P<0.0005). No adverse reactions were observed from the two interventions. Conclusion: Paring followed by IPL did not differ significantly from paring alone in clearance of recalcitrant hand and foot warts but caused significantly more pain.

show abstract

Section: Discussionmentioning

confidence: 99%

“…However, pain of mild to moderate intensities related to IPL is a known adverse effect [23][24][25]. The IPLsystem used in this trial did not use cooling of the epidermis, which is utilized in newer IPL-systems to minimize treatment-related pain [22][23][24][25].…”

Section: Discussionmentioning

confidence: 99%

Paring and intense pulsed light versus paring alone for recalcitrant hand and foot warts: A randomized clinical trial with blinded outcome evaluation

Togsverd‐Bo¹,

Gluud²,

Winkel³

et al. 2010

Lasers Surg Med

View full text Add to dashboard Cite

show abstract

“…13) Other authors reported similar positive results for photorejuvenation with dominant vascular pattern. 4,14,15) The vascular lesions treated in this study were port wine stains and angiomas, which were treated using IPL technology. For telangiectasias, however, we preferred using the Yag laser mode, holding the head at a 45 degree angle; in these cases, patients reported a satisfaction rate of over 90%.…”

Section: Discussionmentioning

confidence: 99%

The Aesthetic Applications of Intense Pulsed Light Using the Lumenis M-22 Device

2011

View full text Add to dashboard Cite

Background: Fifteen years have passed since the first Intense Pulsed Light (IPL) devices were introduced into the market. A variety of devices that use light energy for aesthetic puposes are currently manufactured by several companies, and newer devices offering improved performance and features are periodically being introduced. Herein we present our experience with the MP-22 device (Lumenis Ltd.,Yokneam, Israel) for cosmetic treatment of benign skin lesions. Patients and Methods:We collected patient data from all patients who received IPL and Nd:Yag laser treatments with the MP-22 over a one year period (Jan 2009 -Jan 2010). The study group included 92 patients who were treated on the face, neck, trunk and hands. The main indications for treatment were lentigo and superficial vascular lesions. Patient age ranged from 16 to 72 years old, and 89 patients were female. Exclusion criteria for treatment were suspicion of skin cancer, isotretinoin treatment during the previous 6 months, and pregnancy. Satisfaction after treatment was evaluated by the patients on a scale ranging from 0 to 5, with 5 = excellent, 4 = very good, 3= good, 2= moderate improvement, 1= mild improvement and 0= no improvement. Results: Ninety-three percent of the patients were satisfied (rating 3, 4 or 5 on the above scale). Ninety-five percent of the patients had one or two treatment sessions. Of the treatments, 82 were on the face, two on the neck, four on the trunk and 13 on the dorsal aspect of the hands. Minor side effects such as erythema for longer than 24 hours and facial edema for more than one day were reported by 9 patients. Major complications such as scars, hyperpigmentation or hypopigmentation were not recorded. The fluence delivered varied from 14 -18 J/cm 2 . Conclusion: IPL is an effective and safe method for skin treatments, namely removal of vascular and pigmented lesions.

show abstract

“…Even though medical treatments for the disease are commonly performed including topical preparations such as urea ointment, salicylic acid petrolatum, vitamin A ointment, Vitamin A/D ointment, and Vitamin A ingested orally, these approaches, which are hard to be evaluated as successful from our experience, often result in forcing patients to wait until the spontaneous regression of the condition. In recent years, procedures using various types of low fluence lasers have been widely used with devfices based on pulsed light sources, or radiofrequency (RF) energy, as a skin rejuvenation approach to refresh the skin and improve follicular dilatation, and the results have been reported [4][5][6][7] . Initially, the effect of low level laser therapy (LLLT) on skin had been reported as an action to enhance the treatment of recalcitrant ulcers and accidental or iatrogenic trauma 8) using the effect of biostimulation or photobioactivation 9) but it became to be referred to as photo-rejuvenation therapy 10, 11) later due to the skin rejuvenation effect.…”

Section: Discussionmentioning

confidence: 99%

Treatment of lichen pilaris with a Q-switched Nd:YAG laser in quasi long-pulsed mode: A case report (a secondary publication)

Ueda¹

2014

LASER THERAPY

View full text Add to dashboard Cite

Even though lichen pilaris has been conventionally treated with topical preparations such as urea ointment, salicylic acid, petrolatum and vitamin A ointment and the like, none of these therapeutic approaches has been reported to achieve good and consistent results. In addition, this may be a disorder for which the necessity for treatment tends to be underestimated since the symptoms are is said to decrease with age and almost disappear spontaneously by the time the patients are in their 30s. However, spontaneous regression can take a longer period of time till full disappearance, prompting quite a few patients to visit clinics from the cosmetic perspective of the condition. The Q-switched Nd: YAG laser (QSNY) has been wellreported for the successful treatment of pigmented cutaneous lesions and for skin rejuvenation. The present study therefore trialled the application of the QSNY in a case of lichen pilaris. Only a few treatments have been reported as significantly effective, so often natural resolution over time is the only option. The present study examined the use of a 1064 nm Q-switched Nd:YAG laser (QSNY) in quasi long-pulsed mode, in an attempt to treat a case of lichen pilaris. Subject and Methods Subject and condition Subject and Methods:A 33-year-old male presented with light-brown aggregated papules observed on both sides of the upper arms. The affected areas were treated every other week (QSNY, pulse width 300 µs, pulse energy 3.0 J/cm², spot size 6 mm and repetition rate 10 Hz). Clinical photography was taken of the lesions at baseline and three months after the final treatment in addition to macrophotography and 3-D photography, biopsies being taken at both time points for histological comparison. Results:The clinical photography and objective image evaluation demonstrated shrinkage of pores and improvement of the unevenness of the skin. Histological examination suggested that the effect of the micropulsed QSNY on the horny layer, epidermal keratinocytes and dermal collagen resulted in a peeling effect and increased dermal collagen density, which eventually led to the shrinkage of the pores and improvement of the skin condition. Conclusions:The results of this single patient case report suggest that the micropulsed QSNY could be an effective treatment option for lichen pilaris, improvement of which is often difficult.Further studies with an appropriately-sized population are merited to confirm these preliminary results.

show abstract

Full‐face photorejuvenation of photodamaged skin by intense pulsed light with integrated contact cooling: Initial experiences in Asian patients

Cited by 126 publications

References 14 publications

Paring and intense pulsed light versus paring alone for recalcitrant hand and foot warts: A randomized clinical trial with blinded outcome evaluation

Paring and intense pulsed light versus paring alone for recalcitrant hand and foot warts: A randomized clinical trial with blinded outcome evaluation

The Aesthetic Applications of Intense Pulsed Light Using the Lumenis M-22 Device

Treatment of lichen pilaris with a Q-switched Nd:YAG laser in quasi long-pulsed mode: A case report (a secondary publication)

Contact Info

Product

Resources

About