Recently, there has been a growing interest in biodiesel due to its utilization of renewable resources, which is particularly significant given the increasing depletion of fossil fuel stocks. The utilization of Cresson weed in biodiesel fuel production is a pioneering application of botanical herbs within the biodiesel industry. This study compares the combustion characteristics of biodiesel fuel B10, B20, B40, B60, and D80B10M10 blends with petroleum diesel. This analysis examined the combustion process across various equivalence ratios in semi-industrial boilers. The study examined the combustion efficiency, flue gas emissions (CO, CO 2 , T exhaust, and HC), as well as flame length. The obtained findings show that adding more biodiesel fuel to diesel fuel increases its combustion efficiency above and beyond what is possible with regular diesel fuel at high energy levels. In addition, blends like B60 and other mixtures like D80B10M10 emit lower levels of pollutants, such as CO, than diesel as well as increase T exhaust and CO 2 , which indicates the completion of combustion.