2023
DOI: 10.1016/j.ijbiomac.2023.127449
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Fucoidan may treat jellyfish dermatitis by inhibiting the inflammatory effect of jellyfish venom

Aoyu Li,
Yang Yue,
Rongfeng Li
et al.
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Cited by 3 publications
(4 citation statements)
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“…HaCaT cells, with different concentrations of TE, can trigger inflammatory factors (IL-1β, IL-6, IL-8, and TNF-α) that rapidly reach their highest level in 2 h. Mice blood cytokine protein expression exhibits a dose-dependent trend of increase. Consistent with these results, TE rapidly and strongly triggered an acute inflammatory response ( 6 , 18 , 32 ). In addition, the accumulation and excessive production of ROS in cells results in oxidative stress, which is one of the primary factors reason for inflammatory diseases.…”
Section: Discussionsupporting
confidence: 84%
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“…HaCaT cells, with different concentrations of TE, can trigger inflammatory factors (IL-1β, IL-6, IL-8, and TNF-α) that rapidly reach their highest level in 2 h. Mice blood cytokine protein expression exhibits a dose-dependent trend of increase. Consistent with these results, TE rapidly and strongly triggered an acute inflammatory response ( 6 , 18 , 32 ). In addition, the accumulation and excessive production of ROS in cells results in oxidative stress, which is one of the primary factors reason for inflammatory diseases.…”
Section: Discussionsupporting
confidence: 84%
“…Under homeostatic conditions, a dynamic equilibrium of mechanisms that generate and remove ROS maintains the redox state of cells ( 33 ). When mice received Nemopilema nomurai, the levels of MDA and glutathione (GSH) significantly increased ( 18 ). Our fluorescence microscopy analysis further indicated that TE dose-dependently induced a significant increase in intercellular ROS and MDA accumulation, which aggravated the lipid peroxidation response.…”
Section: Discussionmentioning
confidence: 99%
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