Fruits and Vegetable Functional Foods

Gasparre, Nicola; Rosell, Cristina M.

doi:10.1002/9781119776345.ch6

Cited by 1 publication

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References 144 publications

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“…Functional foods which can be natural or processed foodstuffs for basic consumption in the diet provide an essential nutritional level and also share potentially positive effects on the host's health by optimizing the immune system and reducing the incidence of diseases. 26 Gasparre and Rossel, 27 reported on increased efforts by the food industry to incorporate nutritional enrichment strategies with plant-based ingredients (phytochemicals) into foods such as bakery products, pasta-like products, snacks, and beverages to increase the public's vegetable intake, thereby increasing the availability of their bioactive components, which play critical roles in biological systems. Cyanide content was higher in the basal (control) diet compared to the HFD groups.…”

Section: Resultsmentioning

confidence: 99%

Effect of Sub-chronic Dietary Vernonia amygdalina in Monosodium Glutamate and High-fat Diet Fed Male Wistar Rats on Antioxidant Status and other Biochemical Parameters

2024

TJNPR

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Monosodium glutamate (MSG) has been shown to have a flavour-enhancing effect in foods, however, its safety and systemic side effects have not been fully clarified. Vernonia amygdalina (VA) is a medicinal plant used in traditional medicines. This study evaluated the effects of MSG intoxication on antioxidant status, renal histopathology, and other biochemical markers in Wistar rats given a high-fat diet (HFD), as well as the effects of VA. Male Wistar rats (36) were randomly allocated into six groups of six rats each, with average weights ranging from 150 to 220 grams.5%, 10% dietary incorporated VA, and Orlistat 10 mg/kg were given to the animals for 4 weeks after treatment with MSG 8000 mg/kg orally for the first 8 weeks while on HFD. The control group and HFD group received basal (control) diet and HFD for 12 weeks respectively while the MSG group received MSG 8000 mg/kg for 8 weeks and basal (control) diets for 12 weeks. MSG increased urea and creatine levels while a 10% VA diet reduced it significantly, MSG also reduced liver catalase (CAT) enzyme while Orlistat 10 mg/kg was > than 5% and 10% VA in restoring it. HFD increased liver Malondialdehyde (MDA) while 10% VA diet was > than 5% VA and Orlistat 10 mg/kg in antioxidant effect. MSG increased brain superoxide (SOD) similar to a 10% VA diet. Nephrotoxicity was prominent in the MSG group while dietary incorporation of VA provided some benefit.VA ameliorated the deleterious effects observed with MSG +HFD co-intoxication and could provide benefits in MSG and HFD-induced antioxidant depletion.

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Section: Resultsmentioning

confidence: 99%

Effect of Sub-chronic Dietary Vernonia amygdalina in Monosodium Glutamate and High-fat Diet Fed Male Wistar Rats on Antioxidant Status and other Biochemical Parameters

2024

TJNPR

View full text Add to dashboard Cite

show abstract

Fruits and Vegetable Functional Foods

Cited by 1 publication

References 144 publications

Effect of Sub-chronic Dietary Vernonia amygdalina in Monosodium Glutamate and High-fat Diet Fed Male Wistar Rats on Antioxidant Status and other Biochemical Parameters

Effect of Sub-chronic Dietary Vernonia amygdalina in Monosodium Glutamate and High-fat Diet Fed Male Wistar Rats on Antioxidant Status and other Biochemical Parameters

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