Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis

Cooper, Andrew; Forouhi, Nita G.; Ye, Z.; Buijsse, Brian; Arriola, Larraitz; Balkau, Beverley; Barricarte, Aurelio; Beulens, Joline W.J.; Boeing, Heiner; Büchner, Frederike L.; Dahm, Christina C.; Lauzon-Guillain, Blandine de; Fagherazzi, Guy; Franks, Paul W.; González, Carlos; Grioni, Sara; Kaaks, Rudolf; Key, Timothy J.; Masala, Giovanna; Navarro, Carmen; Nilsson, Peter M.; Overvad, Kim; Panico, Salvatore; Quiŕos, J. Ramón; Rolandsson, Olov; Roswall, Nina; Sacerdote, Carlotta; Sánchez, María‐José; Slimani, Nadia; Sluijs, Ivonne; Spijkerman, Annemieke M.W.; Teucher, Birgit; Tjønneland, Anne; Tumino, Rosario; Sharp, Stephen J.; Langenberg, Claudia; Feskens, Edith J. M.; Riboli, Elio; Wareham, Nick

doi:10.1038/ejcn.2012.85

Cited by 235 publications

(240 citation statements)

References 49 publications

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“…Several studies of the present meta-analysis used MD scores based on Trichopoulou et al with only slight variations. The combination of components and the adherence to the whole concept of an MD seems pivotal: increasing fruit and vegetable intake as a sole option only showed weak overall effects on risk for developing T2DM (31) . Making use of synergistic effects of different nutrient compounds especially in an MD has shown to be more distinct and effective.…”

Section: Discussionmentioning

confidence: 99%

Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis

Schwingshackl

Missbach

König

et al. 2014

Public Health Nutr.

264

182

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Objective: Adherence to a Mediterranean diet is associated with significant improvements in health status. However, to date no systematic review and metaanalysis has summarized the effects of Mediterranean diet adherence on the risk of type 2 diabetes mellitus. Design: Electronic searches for randomized controlled trials and cohort studies were performed in MEDLINE, SCOPUS, EMBASE and the Cochrane Trial Register until 2 April 2014. Pooled effects were calculated by an inverse-variance randomeffect meta-analysis using the statistical software Review Manager 5·2 by the Cochrane Collaboration. Setting: Meta-analysis of randomized controlled trials and cohort studies. Subjects: Eligibility criteria: 19+ years of age. Results: One randomized controlled trial and eight prospective cohort studies (122 810 subjects) published between 2007 and 2014 were included for metaanalysis. For highest v. lowest adherence to the Mediterranean diet score, the pooled risk ratio was 0·81 (95 % CI 0·73, 0·90, P < 0·0001, I 2 = 55 %). Sensitivity analysis including only long-term studies confirmed the results of the primary analysis (pooled risk ratio = 0·75; 95 % CI 0·68, 0·83, P < 0·00001, I 2 = 0 %). The Egger regression test provided no evidence of substantial publication bias (P = 0·254). Conclusions: Greater adherence to a Mediterranean diet is associated with a significant reduction in the risk of diabetes (19 %; moderate quality evidence). These results seem to be clinically relevant for public health, in particular for encouraging a Mediterranean-like dietary pattern for primary prevention of type 2 diabetes mellitus.

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Section: Discussionmentioning

confidence: 99%

Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis

Schwingshackl

Missbach

König

et al. 2014

Public Health Nutr.

264

182

View full text Add to dashboard Cite

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“…Cooper et al (44) have since published a similar metaanalysis to Carter et al (43) but included their own data from a large case-cohort study, the EPIC-InterAct study.…”

Section: Ecological/modelling Studiesmentioning

confidence: 99%

Fruit and vegetable intake and risk of cardiovascular disease

2013

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A high intake of fruit and vegetables (FV) has been shown to be associated with reduced risk of a number of chronic diseases, including CVD. This review aims to provide an overview of the evidence that increased FV intake reduces risk of CVD, focusing on studies examining total FV intake. This evidence so far available is largely based on prospective cohort studies, with meta-analyses demonstrating an association between increased FV intake and reduced risk of both CHD and stroke. Controlled intervention trials examining either clinical or cardiovascular risk factor endpoints are scarce. However, such trials have shown that an increase in FV consumption can lower blood pressure and also improve microvascular function, both of which are commensurate with a reduced risk of CVD. The effects of increased FV consumption on plasma lipid levels, risk of diabetes and body weight have yet to be firmly established. In conclusion, evidence that FV consumption reduces the risk of CVD is so far largely confined to observational epidemiology, with further intervention studies required.

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“…A large cross-European prospective study involving 8 countries through the European Prospective Investigation into Cancer and Nutrition-InterAct did not find any significant associations between fruit intake and T2D risk (87). Similarly, this updated meta-analysis did not note any significant associations between fruit intake and T2D risk.…”

Section: Epidemiologic Studies: Fruit Yogurt and Cardiometabolic Hementioning

confidence: 77%

Potential Health Benefits of Combining Yogurt and Fruits Based on Their Probiotic and Prebiotic Properties

Fernandez

Marette

2017

Advances in Nutrition

117

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Fruit and yogurt have been identified individually as indicators of healthy dietary patterns. Fruits are relatively low in energy density and are an excellent source of antioxidants and prebiotic fibers and polyphenols, which can promote digestive health. Yogurt, on the other hand, is a nutrient-dense food that is a good source of dairy protein, calcium, magnesium, vitamin B-12, conjugated linoleic acid, and other key fatty acids. In addition, it contains beneficial bacterial cultures, making it a potential source of probiotics. Yogurt's unique fermented food matrix provides added health benefits by enhancing nutrient absorption and digestion. Combining the intake of yogurt and fruit could provide probiotics, prebiotics, high-quality protein, important fatty acids, and a mixture of vitamins and minerals that have the potential to exert synergistic effects on health. Yogurt consumption has been associated with reduced weight gain and a lower incidence of type 2 diabetes, whereas fruits have established effects on reducing the risk of cardiovascular disease. Yogurt and fruits can be eaten together and may exert combined health benefits through potential prebiotic and probiotic effects. Furthermore, substituting high-energy, nutrient-deficient snacks with fruit and yogurt could reduce the intake of high-calorie obesogenic foods. In light of the positive cardiometabolic impacts of fruit and yogurt and their association with healthy dietary patterns, there is sufficient evidence to warrant further exploration into the potential synergistic health benefits of a combined intake of fruit and yogurt. Adv Nutr 2017;8(Suppl):155S-64S.

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Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis

Cited by 235 publications

References 49 publications

Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis

Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis

Fruit and vegetable intake and risk of cardiovascular disease

Potential Health Benefits of Combining Yogurt and Fruits Based on Their Probiotic and Prebiotic Properties

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