Frühe und präsymptomatische Erkennung der Chorea Huntington

Leblhuber, Friedrich

doi:10.1055/s-2007-999115

Cited by 7 publications

(1 citation statement)

References 62 publications

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“…EKG, EEG, er bzw. MRT und SPECT-Untersuchungen mit HMPAO als Tracer wurden durchgeführt [4,24,42). Bei den morphologischen und funktionellen Untersuchungen legten wir besonderes Augenmerk auf frontal betonte Atrophie bzw.…”

Section: Patienten Und Methodeunclassified

Frontallappen-Demenzen

Zachhuber¹,

Leblhuber²,

Bancher³

et al. 1999

Fortschr Neurol Psychiatr

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Frontal lobe dementia (FLD) is characterised clinically by personality changes and a progressive speech disorder finally leading to mutism. In the course of the disease also other neurological syndromes may occur such as parkinsonism, a partial Klüver-Bucy-syndrome or a degeneration of motoneurons (FLD + MND). The latter leads to death within about three years. The clinical diagnosis of FLD is supported by functional (SPECT) and morphological (CT, MRI) investigations. From 1988 to 1997, 9 cases of FLD (6 female, 3 male) were clinically diagnosed at our department of Gerontology, LNK Linz. In two of these cases the clinical diagnosis was confirmed histopathologically. Characteristically, all except one patients showed a presenile beginning of the disease. The clinical course was slowly progressive with a mean duration of about 10 years. Special attention was given to additional signs and symptoms of motor neuron disease, parkinsonism and hyperorality. Six patients suffered from FLD + MND; parkinsonism (rigid-akinetic type) and a partial Klüver-Bucy-syndrome were diagnosed in 5 cases each. In histopathological investigations the incidence of FLD seems to increase. This type of dementia should be considered as an important diagnosis differential of presenile dementia-syndromes.

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Section: Patienten Und Methodeunclassified

Frontallappen-Demenzen

Zachhuber¹,

Leblhuber²,

Bancher³

et al. 1999

Fortschr Neurol Psychiatr

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Demenz bei Morbus Huntington

Przuntek¹,

Filger-Brillinger²

1996

Therapie Im Grenzgebiet Von Psychiatrie Und Neurologie

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Psychomotor disturbances in psychiatric patients as a possible basis for new attempts at differential diagnosis and therapy

Günther

Streck²,

Müller³

et al. 1995

Eur Arch Psychiatry Clin Nuerosci

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Parts I-III of this series established signs of disturbed motor performance--the "psychotic motor syndrome" (PMS)--in schizophrenic and endogenous depressed patients, which was not found in neurotic/reactive depressed nor healthy persons. Part IV yielded EEG signs of concomitant brain dysfunction in these patients, which were demonstrated by other (SPECT/PET) neuroimaging methods also. In part V we engaged in the development of motor-training programs applied both actively and mentally, using the PMS as target syndrome in depressed patients. We hypothesized that motor training would not only improve disturbed motor behaviour, but ameliorate other symptoms of psychopathology additionally, which was supported for these patients. Part VI is the final paper of this series demonstrating favourable results of our motor-training programs in 96 schizophrenic inpatients in two separate investigations. A general discussion to the whole series attempts to link motor symptoms to neuroimaging findings of brain dysfunction during motor challenge and to modern three- and four-factor models of schizophrenic symptomatology. A final version of our complete training programs will be published as an appendix to this paper along with information regarding the abbreviated test battery.

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Frühe und präsymptomatische Erkennung der Chorea Huntington

Cited by 7 publications

References 62 publications

Frontallappen-Demenzen

Frontallappen-Demenzen

Demenz bei Morbus Huntington

Psychomotor disturbances in psychiatric patients as a possible basis for new attempts at differential diagnosis and therapy

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