Frugal Science Powered by Curiosity

Byagathvalli, Gaurav; Challita, Elio J.; Bhamla, M. Saad

doi:10.1021/acs.iecr.1c02868

Cited by 18 publications

(21 citation statements)

References 58 publications

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“…The extraordinary feature of foldscope is that can instead of an eyepiece, a small lens is attached to the sheet where it can be attached to the smartphone camera (Anderson, 2018), that was magnetically docked to the foldscope to achieve 140×–2000× magnification (Cybulski et al, 2014). Foldscope can be assembled less than in a minute and the adjustments can be performed along all three dimensions, that is, X , Y , and Z ‐axis with its weight of almost 8.8 g are trivial able to put into a pocket (70 × 20 × 2 mm 3 ) (Cybulski et al, 2014; Mathews, 2014) and amenable with on‐site field studies. Additionally, with the help of HDMI connectivity and a TV module, the foldscope image that was displayed on the smartphone screen may be viewed on a TV monitor, allowing for quick digitalization of slides for viewing, exhibition, communication, and storing (Prakash & Prakash, 2019).…”

Section: Alternative To Conventional Microscopesmentioning

confidence: 99%

“…Bright field, darkfield, fluorescence, and lens‐array imaging are all possible with foldscope (Cybulski et al, 2014). This variable imaging capability of foldscope over conventional microscopes is an ideal advantage.…”

Section: Alternative To Conventional Microscopesmentioning

confidence: 99%

“…Foldscope visitors interact with the microcosmos forum (http://www.http/microcosmos.com) and share their data, observations, opinions, and challenges by uploading images and time‐lapse videos (Cybulski et al, 2014). Students can also use foldscopes to communicate, gain inspiration, and learn from other explorers.…”

Section: Alternative To Conventional Microscopesmentioning

confidence: 99%

“…For example, many South African schools lack access to high‐quality teaching tools, such as laboratory equipment for hands‐on learning in the Life Sciences classroom (Mampane & Bouwer, 2011). In education, “frugal science” is a concept that brings low‐cost, easily accessible scientific instructional instruments to underdeveloped countries (Ahuja, 2014; Byagathvalli et al, 2021; Veeraraghavan & Silverstein, 2021).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Foldscope microscope, an inexpensive alternative tool to conventional microscopy—Applications in research and education: A review

Ganesan

Christyraj

Venkatachalam

et al. 2022

Microscopy Res & Technique

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Microscope is a device used for the visualization of tiny objects which are not visible to the naked eye. Traditional microscopes have been crucial for the advancement of contemporary science and medicine. Recent advancements in the field of microscopy have fueled its exponential growth rate. However, due to their expensive cost and complicated structure, modern microscopes remain inaccessible to the majority of the public. Nonetheless, the foldscope paper microscope has made it possible for anyone to explore and understand the world of microbes and organisms. In this review, we have listed foldscope-based research projects in various domains, as well as their key properties when compared to traditional research microscopes. In addition, we have briefly explored the impact of a foldscope microscope on public health, clinical diagnostics, forensic science, agriculture, basic science, developmental biology, and education. Moreover, the major drawbacks of paper microscopes and the current steps being taken to upgrade foldscope and its features are discussed in this review. Finally, we have concluded with our perspective that the microscope may be updated to imitate the advancement of a conventional microscope. Research Highlights• The foldscope, a low-cost instrument for studying the microscopic world.• Foldscope applications were compared to conventional microscopes in many sectors.• The foldscope microscope's existing limitations and potential prospects are highlighted.

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Section: Alternative To Conventional Microscopesmentioning

confidence: 99%

Section: Alternative To Conventional Microscopesmentioning

confidence: 99%

Section: Alternative To Conventional Microscopesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Foldscope microscope, an inexpensive alternative tool to conventional microscopy—Applications in research and education: A review

Ganesan

Christyraj

Venkatachalam

et al. 2022

Microscopy Res & Technique

View full text Add to dashboard Cite

show abstract

“…As compared to experiments conducted in school laboratories, kitchen experiments have a higher potential for engagement as we encounter them every single day, and since they require very little equipment. They offer a low-cost 'frugal science' alternative that is less susceptible to budget cuts, and more accessible to students from underrepresented socioeconomic backgrounds [953,954].…”

Section: B Learning From Kitchen Experimentsmentioning

confidence: 99%

Culinary fluid mechanics and other currents in food science

Mathijssen¹,

Lisicki²,

Prakash³

et al. 2022

Preprint

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Innovations in fluid mechanics have refined food since ancient history, while creativity in cooking inspires science in return. Here, we review how recent advances in hydrodynamics are changing food science, and we highlight how the surprising phenomena that arise in the kitchen lead to discoveries and technologies across the disciplines, including rheology, soft matter, biophysics and molecular gastronomy. This review is structured like a menu, where each course highlights different aspects of culinary fluid mechanics. Our main themes include multiphase flows, complex fluids, thermal convection, hydrodynamic instabilities, viscous flows, granular matter, porous media, percolation, chaotic advection, interfacial phenomena, and turbulence. For every topic, we first provide an introduction accessible to food professionals and scientists in neighbouring fields. We then assess the state-of-the-art knowledge, the open problems, and likely directions for future research. New gastronomic ideas grow rapidly as the scientific recipes keep improving too.

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3D printing‐based frugal manufacturing of glass pipettes for minimally invasive delivery of therapeutics to the brain

Qiao,

Gulisashvili,

Jablonska

et al. 2023

Neuroprotection

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ObjectiveIntracerebral delivery of agents in liquid form is usually achieved through commercially available and durable metal needles. However, their size and texture may contribute to mechanical brain damage. Glass pipettes with a thin tip may significantly reduce injection‐associated brain damage but require access to prohibitively expensive programmable pipette pullers. This study is to remove the economic barrier to the application of minimally invasive delivery of therapeutics to the brain, such as chemical compounds, viral vectors, and cells.MethodsWe took advantage of the rapid development of free educational online resources and emerging low‐cost 3D printers by designing an affordable pipette puller (APP) to remove the cost obstacle.ResultsWe showed that our APP could produce glass pipettes with a sharp tip opening down to 20 μm or less, which is sufficiently thin for the delivery of therapeutics into the brain. A pipeline from pipette pulling to brain injection using low‐cost and open‐source equipment was established to facilitate the application of the APP.ConclusionIn the spirit of frugal science, our device may democratize glass pipette‐puling and substantially promote the application of minimally invasive and precisely controlled delivery of therapeutics to the brain for finding more effective therapies of brain diseases.

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Frugal Science Powered by Curiosity

Cited by 18 publications

References 58 publications

Foldscope microscope, an inexpensive alternative tool to conventional microscopy—Applications in research and education: A review

Foldscope microscope, an inexpensive alternative tool to conventional microscopy—Applications in research and education: A review

Culinary fluid mechanics and other currents in food science

3D printing‐based frugal manufacturing of glass pipettes for minimally invasive delivery of therapeutics to the brain

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