Fructose vs. glucose: modulating stem cell growth and function through sugar supplementation
Salaheldeen Elsaid,
Xiangdong Wu,
Sui Seng Tee
Abstract:In multicellular organisms, stem cells are impacted by microenvironmental resources such as nutrient availability and oxygen tension for their survival, growth, and differentiation. However, the accessibility of these resources in the pericellular environment greatly varies from organ to organ. This divergence in resource availability leads to variations in the potency and differentiation potential of stem cells. This study aimed to explore the distinct effects of glucose and fructose, as well as different oxy… Show more
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