Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model

Chi, Liandi; Khan, Imran; Zhou, Lin; Zhang, Jiwen; Lee, Simon Ming‐Yuen; Leong, Waikit; Hsiao, W.L. Wendy; Zheng, Ying

doi:10.1016/j.phymed.2019.153157

Cited by 84 publications

(70 citation statements)

References 49 publications

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“…The literature showing the effects of prebiotics on depressive disorders is much less abundant than the research on probiotics. Chi et al [153] investigated the antidepressant efficacy of fructo-oligosaccharides (FOSs) extracted from Morinda officinalis How., a traditional Chinese herb. They used a chronic unpredictable mild stress model of Sprague Dawley rats and then have introduced FOSs via intragastric gavage [153].…”

Section: Prebiotic Studies 621 Animal Studiesmentioning

confidence: 99%

“…Chi et al [153] investigated the antidepressant efficacy of fructo-oligosaccharides (FOSs) extracted from Morinda officinalis How., a traditional Chinese herb. They used a chronic unpredictable mild stress model of Sprague Dawley rats and then have introduced FOSs via intragastric gavage [153]. The antidepressive properties were assessed through behavioral tests, intestinal morphology and measurements of corticosterone levels [153].…”

Section: Prebiotic Studies 621 Animal Studiesmentioning

confidence: 99%

“…They used a chronic unpredictable mild stress model of Sprague Dawley rats and then have introduced FOSs via intragastric gavage [153]. The antidepressive properties were assessed through behavioral tests, intestinal morphology and measurements of corticosterone levels [153]. Additionally, the bacterial genomic DNA from feces was extracted and gut microbiota profiling was carried out [153].…”

Section: Prebiotic Studies 621 Animal Studiesmentioning

confidence: 99%

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Probiotics, Prebiotics and Postbiotics on Mitigation of Depression Symptoms: Modulation of the Brain–Gut–Microbiome Axis

et al. 2021

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The brain–gut–microbiome axis is a bidirectional communication pathway between the gut microbiota and the central nervous system. The growing interest in the gut microbiota and mechanisms of its interaction with the brain has contributed to the considerable attention given to the potential use of probiotics, prebiotics and postbiotics in the prevention and treatment of depressive disorders. This review discusses the up-to-date findings in preclinical and clinical trials regarding the use of pro-, pre- and postbiotics in depressive disorders. Studies in rodent models of depression show that some of them inhibit inflammation, decrease corticosterone level and change the level of neurometabolites, which consequently lead to mitigation of the symptoms of depression. Moreover, certain clinical studies have indicated improvement in mood as well as changes in biochemical parameters in patients suffering from depressive disorders.

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Section: Prebiotic Studies 621 Animal Studiesmentioning

confidence: 99%

Section: Prebiotic Studies 621 Animal Studiesmentioning

confidence: 99%

Section: Prebiotic Studies 621 Animal Studiesmentioning

confidence: 99%

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Probiotics, Prebiotics and Postbiotics on Mitigation of Depression Symptoms: Modulation of the Brain–Gut–Microbiome Axis

et al. 2021

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“…In addition to that, FOS treatment decreased the corticosterone levels in the plasma and urine of the model rats. They concluded that the antidepression efficacy of the FOS depends on the modulation of the gut microbiota [52].…”

Section: Health Benefits and Applicationsmentioning

confidence: 99%

“…Anti-cancer activity [69] Rice Straw Antibacterial activity [66] Grape shoot Diet-induced obesity [60] Lotus seedpod Lipid homeostasis [64] Lotus seedpod Emulsifiers and antioxidants [68] Commiphora Africana Anticancer activity [56] Dragon fruit Gut motility [26] Morinda officinal Depression [52] Flaxseed Antitumor activity [49] Cocoa Beans Antidiabetic activity [70] Carex Species Against Colon Tumorigenic Cells [43] Salvia officinalis Antioxidant properties [42] Peanut Skin Lipid-lowering activity [48] Cyphostemma crotalarioides Antifungal properties [71] F o r p e r s o n a l p r i v a t e u s e o n l y . From an economic point of view, the growing use of plant-derived materials will have environmental benefits, including waste reduction, lower greenhouse gas emissions, rewilding, and others.…”

Section: Adzuki Beansmentioning

confidence: 99%

Research Trends in Plant-Derived Oligomers for Health Applications

Köse

Hardy

Sheridan

et al. 2021

CNT

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Objective: Epidemiological data illustrates that there is a strong relationship between dietary intake of natural bioactive compounds and their beneficial properties against various diseases, and this stimulates academic and industrial interest in using plant-derived compounds for health and medicine. For this reason, recent health related studies in the literature have focused on a variety of many plant-derived bioactive compounds. Even though the bioactivities of such compounds have widely been investigated, there are few studies about oligomeric species and their activities. Methods: In this review, extraction and isolation methods of the plant-derived oligomers and the use of such oligomers in health applications is summarised. Results: In the literature, many studies state that oligomeric compounds have beneficial to human health. To maximize these beneficial properties, various ways to use oligomeric compounds have been examined and summarised. Conclusion: A better understanding of the specific activities of distinct components of plant-derived oligomers is expected to open new avenues for drug discovery. This review gives an overview of oligomers with health beneficial properties and their possible applications in healthcare.

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The Leap of Inulin Fructans from Food Industry to Medical Application

Zhou

Wang

et al. 2023

Chemistry & Biodiversity

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As a dietary supplement, the efficacy of prebiotics has become a hot issue in recent years. Inulin is one of internationally recognized prebiotics and belongs to a group of non‐digestible and fermentable carbohydrates. Currently, the food industry is increasingly using prebiotic inulin as a health‐promoting substrate, not just as food supplement. In addition, inulin has also shown great promise in the treatment of various diseases. This article reviews the application of inulin in the food industry and summarizes physiological function of inulin. Through the review and prospect of the research on obesity, diabetes and mental illness, it provides the theoretical basis for the joint development of inulin in food industry and medical application.

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Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model

Cited by 84 publications

References 49 publications

Probiotics, Prebiotics and Postbiotics on Mitigation of Depression Symptoms: Modulation of the Brain–Gut–Microbiome Axis

Probiotics, Prebiotics and Postbiotics on Mitigation of Depression Symptoms: Modulation of the Brain–Gut–Microbiome Axis

Research Trends in Plant-Derived Oligomers for Health Applications

The Leap of Inulin Fructans from Food Industry to Medical Application

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