Fructo-oligosaccharides enhance the mineral absorption and counteract the adverse effects of phytic acid in mice

Wang, Yu; Zeng, Tao; Wang, Shue; Wang, Wei; Wang, Qian; Yu, Hui

doi:10.1016/j.nut.2009.04.014

Cited by 74 publications

(41 citation statements)

References 33 publications

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“…Also, prebiotics are known to prevent the colonization of human gut by pathogenic microorganisms because they encourage the growth of beneficial bacteria (Roberfroid 2000b;Mishra and Mishra 2013). As FOS cannot be digested by the enzymes of the small intestine, they are fermented in the large intestine to selectively stimulate the growth of probiotic-like bacteria that are part of the commensal gut microbiota and then produce short-chain fatty acids (SCFAs), mainly acetate, propionate, and butyrate (Yun 1996;Yu Wang et al 2010). It is also importance to notice that long-chain FOS may exert a prebiotic effect in more distal colonic regions compared with the lower-molecular-weight FOS, which may be more quickly fermented in the saccharolytic proximal bowel (Manning and Gibson 2004).…”

Section: Fos Functional Propertiesmentioning

confidence: 99%

“…The importance of zinc (Zn) nurture for growth and development has been widely documented. Marginal Zn deficiency is suspected to be widespread in populations heavily dependent on cereal-based diets containing few animal products (Baba et al 1996;Roberfroid et al 2010;Yu Wang et al 2010).…”

Section: Improving Mineral Adsorptionmentioning

confidence: 99%

“…The main action of FOS is mainly associated with their fermentation by resident microbiota. SCFAs decrease luminal pH and thus create an acidic environment more favorable for mineral solubility (GudielUrbano and Goñi 2002;Yu Wang et al 2010). Another way to contribute to the enhanced mineral absorption is the trophic effect of prebiotics on the gut (cell growth and functional enhancement of the absorptive area).…”

Section: Improving Mineral Adsorptionmentioning

confidence: 99%

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An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Dominguez

Rodrigues

Lima

et al. 2013

Food Bioprocess Technol

133

107

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Over the past years, many researchers have suggested that deficiencies in the diet can lead to disease states and that some diseases can be avoided through an adequate intake of relevant dietary components. Recently, a great interest in dietary modulation of the human gut has been registered. Prebiotics, such as fructooligosaccharides (FOS), play a key role in the improvement of gut microbiota balance and in individual health. FOS are generally used as components of functional foods, are generally regarded as safe (generally recognized as safe status-from the Food and Drug Administration, USA), and worth about 150€ per kilogram. Due to their nutrition-and health-relevant properties, such as moderate sweetness, low carcinogenicity, low calorimetric value, and low glycemic index, FOS have been increasingly used by the food industry. Conventionally, FOS are produced through a two-stage process that requires an enzyme production and purification step in order to proceed with the chemical reaction itself. Several studies have been conducted on the production of FOS, aiming its optimization toward the development of more efficient production processes and their potential as food ingredients. The improvement of FOS yield and productivity can be achieved by the use of different fermentative methods and different microbial sources of FOSproducing enzymes and the optimization of nutritional and culture parameter; therefore, this review focuses on the latest progresses in FOS research such as its production, functional properties, and market data.

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Section: Fos Functional Propertiesmentioning

confidence: 99%

Section: Improving Mineral Adsorptionmentioning

confidence: 99%

Section: Improving Mineral Adsorptionmentioning

confidence: 99%

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An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Dominguez

Rodrigues

Lima

et al. 2013

Food Bioprocess Technol

133

107

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“…2 Besides being a preferred oxidative substrate for colonocytes, SCFAs enhance mineral absorption, provoke enteroendocrine secretions, and stimulate epithelial cell growth and differentiation in the small and large intestine. 29,30 The details of carbohydrate digestion and absorption are discussed in more depth in a recent review by Goodman. 31 Dietary proteins are initially denatured by the acidic environment of the stomach, where parietal cells of the fundus secrete hydrochloric acid, thus lowering the gastric pH.…”

mentioning

confidence: 99%

Pathophysiology of Short Bowel Syndrome

Tappenden

2014

J Parenter Enteral Nutr

156

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The human small intestine is organized with a proximal‐to‐distal gradient of mucosal structure and nutrient processing capacity. However, certain nutrients undergo site‐specific digestion and absorption, such as iron and folate in the duodenum/jejunum vs vitamin B12 and bile salts in the ileum. Intestinal resection can result in short bowel syndrome (SBS) due to reduction of total and/or site‐specific nutrient processing areas. Depending on the segment(s) of intestine resected, malabsorption can be nutrient specific (eg, vitamin B12 or fat) or sweeping, with deficiencies in energy, protein, and various micronutrients. Jejunal resections are generally better tolerated than ileal resections because of greater postresection adaptive capacity than that of the jejunum. Following intestinal resection, energy scavenging and fluid absorption become particularly important in the colon owing to loss of digestive and absorptive surface area in the resection portion. Resection‐induced alterations in enteroendocrine cell abundance can further disrupt intestinal function. For example, patients with end jejunostomy have depressed circulating peptide YY and glucagon‐like peptide 2 concentrations, which likely contribute to the rapid intestinal transit and blunted intestinal adaptation observed in this population. SBS‐associated pathophysiology often extends beyond the gastrointestinal tract, with hepatobiliary disease, metabolic bone disease, D‐lactic acidosis, and kidney stone formation being chronic complications. Clinical management of SBS must be individualized to account for the specific nutrient processing deficit within the remnant bowel and to mitigate potential complications, both inside and outside the gastrointestinal tract.

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“…Varios estudios han evaluado la interacción entre ambos, AF y FOS, y se comprobó que el efecto negativo en la biodisponibilidad de minerales del AF se puede compensar con la ingesta de FOS 55,56 .…”

Section: Estudios Realizados En Animalesunclassified

Prebióticos y su efecto en la biod sponibilidad del calcio

et al. 2011

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En la búsqueda de medidas de prevención de enfermedades crónicas no trasmisibles, se piensa en los prebióticos como una forma efectiva, saludable y relativamente barata para la optimización de la absorción de Ca. El aumento de la expectativa de vida de la población y el incremento de enfermedades como la osteoporosis traen graves consecuencias a la salud del individuo, acarreando importantes desembolsos económicos. En esta revisión se condensa el conocimiento presente sobre el efecto fisiológico del consumo de carbohidratos prebióticos y su posible interferencia en la biodisponibilidad del Ca, como también las posibilidades de su empleo en estrategias para combatir las deficiencias del mineral. Se elaboró una recopilación de los estudios originales realizados con mayor impacto en el tema, dando preferencia a los publicados en los últimos 6 años. Utilizamos las bases de datos PubMed, Lilacs e SciELO, usando las palabras claves calcio, prebióticos e probióticos.Palabras clave: Calcio. Dietética. Minerales. Polisacáridos. Prebióticos. A B S T R A C T

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Fructo-oligosaccharides enhance the mineral absorption and counteract the adverse effects of phytic acid in mice

Cited by 74 publications

References 33 publications

An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Pathophysiology of Short Bowel Syndrome

Prebióticos y su efecto en la biod sponibilidad del calcio

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