Frontispiece: Secondary Structure Tuning of a Pseudoprotein Between β‐Meander and α‐Helical Forms in the Solid‐State

Abstract

Protein Structures In their Research Article (e202113129), Kana M. Sureshan et al. report the secondary structure tuning of a pseudoprotein between β‐meander and α‐helical forms in the solid state.

Rational design and topochemical synthesis of polymorphs of a polymer

“…[38][39][40][41][42][43][44][45][46] We have adopted this methodology for the synthesis of several peptide-based polymers having various secondary structures such as a b-sheet, 47 helix, 48 helical sheet, 49 and b-meander. 50 The b-turn, characterized by an intra-chain NH/CO H-bond between the ith and i + 3rd amino acids, is the third most important secondary structure found in proteins and peptides aer helices and bstrands. b-Turns are known to adopt at least nine different conformations (types I, II, VIII, I ′ , II ′ , Via1, Via2, Vib, and IV) having different dihedral angles of i + 1 and i + 2 positions of the turn.…”

Single-crystal polymers (SCPs): from 1D to 3D architectures

“…Various reaction types have been successfully employed, including [2+2], [72][73][74][75][76][77] [4+4], 9,78-81 diene or triene polymerization, [82][83][84] quinodimethane polymerization, 85,86 acetylenes polymerization [87][88][89][90][91][92] and azide-alkyne cycloaddition. [93][94][95][96][97][98][99] The examples of 1D SCPs obtained by SCSC transformation have also been reviewed in several excellent articles. 67,70,[100][101][102] 2.3.1 [2+2] photo-dimerization.…”

Recent progress in single-crystal structures of organic polymers

“…Besides controlling the crystallization process, topochemical polymerization has also been confirmed as a promising way to prepare single crystals of conjugated polymers. 3,25–49 Topochemical polymerization is a transformation process in the crystal state, where the critical factor is the suitable spatial arrangement of functional groups that are able to form new covalent bonds under the stimulation of light/heat/pressure. 17,25,50–52 Thus, minimizing the impact of newly formed covalent bonds on the structural arrangement while simultaneously maintaining the crystallinity (single crystals) is highly desirable but extremely challenging.…”