Frontispiece: In Vivo Applications of Bioorthogonal Reactions: Chemistry and Targeting Mechanisms

Abstract

Bioorthogonal reactions are biocompatible reactions that enable the study of biomolecules in living organisms. In this review, we summarise and critically appraise recent developments in bioorthogonal reactions for in vivo applications. Areas of focus are the chemical reactions, and the targeting mechanisms used to deliver the bioorthogonal reactions’ components. For more details, see the Review by M. M. A. Mitry, F. Greco and H. M. I. Osborn (DOI: 10.1002/chem.202203942).