“…The degrees of dystonia and rigidity were less strongly associated with cognitive deficits (see Table 5 ). This is reasonable, because the brain regions involved in motor and cognitive performance are the regions that are predominantly affected by the neurodegenerative process in HD ( Bonelli & Cummings, 2007 ; Georgiou-Karistianis et al., 2013 ; Rüb et al., 2015 ) and the cortical loops serve to coordinate motor and cognitive function integrated in the basal ganglia ( Alexander, 1986 ; Klempíř, Klempířová, Štochl, Špačková, & Roth, 2009 ; Ross, Pantelyat, Kogan, & Brandt, 2014 ). Moreover, our findings seem to be consistent with clinical practice and studies, which demonstrated that motor impairment, especially bradykinesia, is a factor contributing to the decline in cognitive performance of HD ( Baake et al., 2017 ; Long et al., 2014 ; van Vugt et al., 2004 ).…”