Frontal lobe inputs to primate motor cortex: evidence for four somatotopically organized ‘premotor’ areas

Muakkassa, Kamel F.; Strick, Peter L.

doi:10.1016/0006-8993(79)90928-4

Cited by 588 publications

(274 citation statements)

References 12 publications

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“…Activity changes within cingulate sulcal areas were thus similar to those observed in primary motor areas. Movement-related activity in caudal cingulate cortex cells in monkeys (Shima et al 1991), close anatomical connections between cingulate motor areas and primary motor cortex again in monkeys (Muakkassa and Strick 1979;Dum and Strick 1991) and a covariation of rCBF levels in cingulate sulcal areas and primary sensorimotor area during force control in humans (Dettmers et al 1995) support the notion that caudal cingulate areas are involved in elementary processes of movement control in monkeys and humans. Why, then, did we not observe a further increase in cingulate activity during bimanual in-phase movements over and above that which would be expected from the combined unimanual conditions, even though the actual movement execution now has to be coordinated between both sides?…”

Section: Ventral Medial Wall Areasmentioning

confidence: 55%

Cerebral midline structures in bimanual coordination

Stephan

Binkofski

Posse

et al. 1999

Experimental Brain Research

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In six healthy right-handed volunteers, we compared the cerebral activation pattern related to unimanual right-and left-hand movements and to bimanual in-phase and anti-phase movements using functional magnetic resonance imaging (fMRI). Internally paced unimanual finger-to-thumb opposition movements led to a strong contralateral activation of primary sensorimotor areas in all six subjects. Midline activity was lateralized to the left side during right-hand movements, but to both sides during left-hand movements. Activity patterns of bimanual in-phase movements resembled the combined activity patterns of the two unimanual conditions: right and left hemispheric activations of the primary sensorimotor cortices and predominantly left-sided medial frontal activity. In contrast, during anti-phase movements, we observed a clear increase in activity, in both right and left frontal midline areas and in right hemispheric, mainly dorsolateral premotor areas compared to in-phase movements. These results indicate that frontal midline activity is not specific for bimanual movements per se. It can already be involved during simple unimanual movements but becomes progressively more involved during more complex aspects of movement control.

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Section: Ventral Medial Wall Areasmentioning

confidence: 55%

Cerebral midline structures in bimanual coordination

Stephan

Binkofski

Posse

et al. 1999

Experimental Brain Research

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“…However, neurons with receptive fields that extend into space for the whole body have also been identified (Hyvärinen 1981;Duhamel et al 1998;Jiang et al 2013). Further, some neurophysiological evidence in monkeys suggests that the dorsal areas of the ventral premotor cortex (Muakkassa and Strick 1979;Kurata et al 1985;Kurata 1989) and medial regions of area 7 (Hyvärinen 1981) might be responsible for a 'foot-centered' PPS network, though an investigation using dynamic sensory stimuli was never formally reported. Thus, behavioural studies have uncovered the presence of PPS around the legs and feet (Schicke and Röder 2006;Schicke et al 2009;Van Elk et al 2013;Pozeg et al 2015;Scandola et al 2016;Stettler and Thomas 2016), but no study, to the best of our knowledge, has specifically examined how far PPS extends for the lower body.…”

Section: Discussionmentioning

confidence: 99%

Peripersonal space boundaries around the lower limbs

et al. 2017

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“…At lateral levels, callosal cells occupied almost the entire rostrocaudal extent of the frontal lobe, from the cortex of the more superficial part of the posterior bank of the arcuate sulcus (AS; area 6) to that buried in the rostra1 bank of the central sulcus (CS; area 4). This region, which contains the representations of orofacial structures (Woolsey et al, 1950;Clark and Luschei, 1974;Muakkassa and Strick, 1979;McGuinnes et al, 1980;Sessle and Wiesendanger, 1982;Gould et al, 1986;Matelli et al, 1986), was devoid of frontoparietal association neurons. Gould et al (1986) described in the owl Figure 3.…”

Section: Tangential Distribution Of Callosal and Association Neuronsmentioning

confidence: 99%

Segregation and overlap of callosal and association neurons in frontal and parietal cortices of primates: a spectral and coherency analysis

et al. 1989

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The spatial relations between selected classes of association and callosal neurons were studied in the frontal and parietal lobes of the macaque monkey using retrogradely transported fluorescent dyes. Fast blue and nuclear yellow were injected in the left frontal (areas 4 and 6) and right posterior parietal (area 5) cortices, respectively. These injections led to the retrograde labeling, in the right frontal cortex, of callosal neurons projecting homotopically and association neurons projecting to ipsilateral area 5; in the left superior parietal lobule, of callosal neurons projecting to contralateral area 5 and association neurons projecting to the ipsilateral frontal lobe. In both frontal and parietal cortices, callosal and association neurons were located in layers III and V-VI; a few neurons were also found in layer II. The contribution of layers V-VI to the callosum was significantly higher in areas 4 and 6 than in area 5. Only a small number of neurons (less than 1%) were double labeled. Spectral analyses were used to characterize the spatial periodicities of the distributions of callosal and association neurons. In areas 4, 6, and 5, both association and callosal spectra were dominated by a strong elevation in the range of low spatial frequencies, corresponding to periodicities in cell density with a peak-to-peak distance of about 8 mm. This indicated an arrangement of these corticocortical cells in the form of bands. The latter displayed various shapes and orientations and were composed of more discrete assemblies of cell clusters of about 400–1000 microns width. Their presence was revealed in the power spectra by a small elevation in the range of high spatial frequencies. The coherency analysis assessed the degree of linear relationships for each spatial frequency, and therefore the degree of similarity, between callosal and association cell distributions, together with their phase relations. Little coherency was found in areas 4 and 6 between bands of callosal and association neurons, which suggests that the 2 cell populations are differently and independently distributed in the tangential domain, with no simple phase relations. The overall mean coherency was higher in area 5 than in the frontal cortex: callosal and association bands were more similar in shape, with more extensive zones of overlap. These data indicate that callosal and association neurons share common principles of spatial organization despite the great regional variability of their interrelations in the tangential cortical domain.(ABSTRACT TRUNCATED AT 400 WORDS)

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Frontal lobe inputs to primate motor cortex: evidence for four somatotopically organized ‘premotor’ areas

Cited by 588 publications

References 12 publications

Cerebral midline structures in bimanual coordination

Cerebral midline structures in bimanual coordination

Peripersonal space boundaries around the lower limbs

Segregation and overlap of callosal and association neurons in frontal and parietal cortices of primates: a spectral and coherency analysis

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