Frontal lobe epilepsy: Clinical syndromes and presurgical evaluation

Riggio, Silvana

doi:10.1016/0896-6974(95)00029-d

Cited by 6 publications

(3 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this retrospective, nonrandomized study, we report our experience in 37 patients with pathologically verified tumoral frontal lobe epilepsy, who were surgically treated and had >1 year of follow-up. Seizures of frontal lobe origin are generally brief, frequent, and often occur in clusters (26). Almost half the patients in our group had auras, a figure somewhat similar to prior studies (19,20).…”

Section: Discussionsupporting

confidence: 90%

Frontal Lobe Tumoral Epilepsy: Clinical, Neurophysiologic Features and Predictors of Surgical Outcome

Zaatreh¹,

Spencer

Thompson³

et al. 2002

Epilepsia

View full text Add to dashboard Cite

Summary:Purpose: To review the clinical, neurophysiologic features and surgical outcomes in patients with frontal lobe tumors and chronic intractable seizures.Methods: Medical records of patients with intractable epilepsy who underwent resection or stereotactic biopsy of frontal lobe tumor (confirmed by surgical pathology) seen between 1985 and 1999 at Yale University School of Medicine Epilepsy Center were reviewed for age at diagnosis, age at onset of seizures, delay between seizure onset and tumor diagnosis, types and frequencies of seizures, EEG results, use of anticonvulsants, extent of surgery, pathological diagnosis, and tumor recurrence.Results: Thirty-seven patients were included. Mean age at seizure onset was 31.6 years, and at tumor diagnosis was 36.2 years. Mean duration between onset of seizures and tumor diagnosis was 6.1 years. Seventeen patients had auras. Seizure frequency averaged 7.6 seizures per week, with 58% of patients having more than one seizure type. All patients used anticonvulsants, with 90% eventually using polytherapy. All patients eventually underwent at least one surgical procedure. Only 13 (35.1%) patients were class I. Twelve (32.4%) patients were class II, seven (18.9%) class III, and five (13.5%) class IV. No statistically significant differences were seen between good and poor long-term seizure outcome in relation to specific tumor pathology, seizure types, or type of resection.Conclusions: Long-term surgical outcomes in tumoral frontal lobe epilepsy are more favorable than those in nontumoral intractable frontal lobe epilepsy (65% class I or II) and less favorable than those in other tumoral epilepsy (overall, 70% class I). Frontal location of intracranial neoplasm may predict a less favorable long-term epilepsy prognosis than tumoral epilepsy in general, an observation for which several explanations are proposed.

show abstract

Section: Discussionsupporting

confidence: 90%

Frontal Lobe Tumoral Epilepsy: Clinical, Neurophysiologic Features and Predictors of Surgical Outcome

Zaatreh¹,

Spencer

Thompson³

et al. 2002

Epilepsia

View full text Add to dashboard Cite

show abstract

“…Ictal grasping has also been observed in other seizure types, but it was either very infrequent (in SMA seizures) or a late and not stereotyped manifestation (in extra‐frontal seizures) (Gardella et al 2006). The cyclic repetition of compulsive motor automatism is a semiological characteristic of frontal hyperkinetic seizures (Wieser et al 1992, Riggio and Harner 1995, Lüders et al 1998, Blume et al 2001). Therefore, we can conclude that repetitive IG is a hallmark of frontal lobe seizures with hyperkinetic motor features.…”

Section: Methodsmentioning

confidence: 99%

Video‐EEG analysis of ictal repetitive grasping in “frontal‐hyperkinetic” seizures

Gardella,

Rubboli,

Tassinari

2006

Epileptic Disorders

View full text Add to dashboard Cite

The aim of this study was to obtain a qualitative and quantitative description of the phenomenon of forced prehension during epileptic seizures (ictal grasping‐ IG) with hyperkinetic semiology. We analysed retrospectively the presurgical, video‐EEG recordings of 35 “frontal hyperkinetic” seizures (FHS) in 14 patients (age range: 9‐48 years) evaluating the features of ictal grasping by means of off‐line, frame‐by‐frame video‐analysis. Ictal grasping was observed in 97.1% of the frontal hyperkinetic seizures in 100% of the patients, with a mean latency of 3.2 seconds with respect to seizure‐onset; a mean number of 7.7 IG per seizure were detected. During the same FHS, both arms could perform IG in an alternating fashion. Grasping was usually preceded by a reaching movement and followed by holding or pulling. The sites of prehension were restricted to relatively few sectors, either on the patient's body (45.5%) or the peri‐personal space (54.5%). In some cases, the grasping was elicited by hand touching. We did not find a consistent relationship between side of hand grasping and side of ictal EEG discharge or MRI lesion. In conclusion, ictal grasping is an extremely frequent clinical manifestation during FHS. It was an early, forced and repetitive motor behavior, without a clear lateralizing value. Ictal grasping appeared with consistent semiological features, similar to voluntary prehension, suggesting a probable ictal release of physiological grasping behavior. [Published with video sequences]

show abstract

“…Significant controversies exist regarding the localizing value of the described symptoms and conflicting reports are endless. The diagnosis is often hampered by the limited access of the scalp-EEG to the frontal extensive network with other parts of the brain and its inability to visualize discharges originating from mesial and orbitofrontal areas [5].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Dilemmas and Management Challenges of Organic Brain Syndrome with Psychiatric Semiology

Awara¹,

Moselhy²,

Sirry³

et al. 2017

JCR

View full text Add to dashboard Cite

Background: Organic brain syndrome could resemble in a protean manner the psychopathology of different psychiatric disorders. Case Report: To share with the scientific community the challenges that professionals face when managing a complex case and also to shed some light on the interface between organic brain syndrome and it's psychiatric and somatic sequelae as illustrated in this case report of a forty-year-old male patient. This case is of particular interest due to the inexplicable multiple somatic and psychiatric complaints that led to numerous hospital admissions and countless investigations. Conclusion: It presented significant clinical challenges to clinicians who have been involved in the management of this patient over the past thirty years. The quandary was in diagnosis and subsequently in treating a difficult to conclude about condition that can be traced back to this patient's early childhood.

show abstract

Frontal lobe epilepsy: Clinical syndromes and presurgical evaluation

Cited by 6 publications

References 63 publications

Frontal Lobe Tumoral Epilepsy: Clinical, Neurophysiologic Features and Predictors of Surgical Outcome

Frontal Lobe Tumoral Epilepsy: Clinical, Neurophysiologic Features and Predictors of Surgical Outcome

Video‐EEG analysis of ictal repetitive grasping in “frontal‐hyperkinetic” seizures

Diagnostic Dilemmas and Management Challenges of Organic Brain Syndrome with Psychiatric Semiology

Contact Info

Product

Resources

About