Frontal fibrosing alopecia and personal care product use: a systematic review and meta-analysis

Kam, Olivia; Na, Sean; Guo, William; Tejeda, Christina I.; Kaufmann, Tara

doi:10.1007/s00403-023-02604-7

Cited by 7 publications

(2 citation statements)

References 30 publications

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“…These chemicals are found in shampoos, conditioners, rebonding agents, hair dyes and others. These chemicals have the potential to cause dermatitis (Kam et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Factors related to contact dermatitis in Makassar City salons

Bumulo,

Nurgahayu,

Syam

2024

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Introduction: contact dermatitis is an inflammation of the skin, generally induced by exposure to extrinsic irritants and allergens. Based on direct interviews conducted by researchers, some salon workers experience contact dermatitis. Symptoms are experienced in the form of small bubbles filled with liquid on the palms of the hands, the skin on the palms feels dry and peeling, and the palms are red and sore due to frequent contact with materials found in the salon. Objective: To determine the factors associated with contact dermatitis in Makassar city salons. Methods: This study used quantitative research methods with a cross-sectional approach. The population in this study was 60 respondents from 7 salons. The sample in this study was 40 workers. The instrument used was a questionnaire. Data analysis using univariate and bivariate analysis. Result: showed that there was a relationship between working period and contact dermatitis (p-value = 0.043 < 0.05), there was a relationship between length of contact with contact dermatitis (p-value = 0.022 < 0.05), there was no relationship between personal hygiene with contact dermatitis (p-value = 1.000 > 0.05), there was no relationship between the use of personal protective equipment (PPE) with contact dermatitis (p-value = 0.638 > 0.05). Conclusion: There is a relationship between the length of work and the length of contact dermatitis in salon workers. It is recommended that salon workers use moisturizer after washing their hands to coat the skin's surface and prevent water loss. Moistors can also be applied to the area affected by dermatitis, which keeps the skin moist so that the recovery process will be faster. Make sure to use a fragrance-free, alcohol-free moisturizer, and hypoallergenic so as not to irritate the skin even more.

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“…These chemicals are found in shampoos, conditioners, rebonding agents, hair dyes and others. These chemicals have the potential to cause dermatitis (Kam et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Factors related to contact dermatitis in Makassar City salons

Bumulo,

Nurgahayu,

Syam

2024

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“…7 Recent candidates for triggering FFA were formalin and cetrimide, both present in several leave-on products, sunscreens, shampoos and moisturizers. [8][9][10] These compounds are reactive with lipids from cell membranes and can damage molecules prompting an autoinflammatory process, which leads to HLA-B expression, impairing the follicular immune privilege. Further investigation on molecular docking for the substances considered candidates in these HLA-B alleles is warranted.…”

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confidence: 99%

HLA‐B alleles associated with frontal fibrosing alopecia in Brazil may share similar peptide presentation and T‐cell interaction profiles

Miot,

Dourado Alves,

Castelli

et al. 2024

Acad Dermatol Venereol

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Dear Editor, Frontal fibrosing alopecia (FFA) become the most prevalent scarring alopecia worldwide, with its incidence significantly increasing in recent decades. 1 The high intrafamilial occurrence (8%-11%) and its association with HLA-B variants (HLA-B*07:02, HLA-B*14:02, B*42:01) suggest genetic susceptibility. [2][3][4][5] This study aimed to explore two Brazilian families with FFA and sporadic, analysing HLA-A, HLA-B, HLA-C and HLA-G genetic variability and the CYP21A2 V281 mutation.

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